Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2024 May 27;9(7):1957-1959.
doi: 10.1016/j.ekir.2024.05.029. eCollection 2024 Jul.

Salt Taste Sensitivity in CKD: Does it Affect Salt Intake?

Mythri Shankar  1 , Qais Al-Awqati  2   3
Affiliations
Editorial

Salt Taste Sensitivity in CKD: Does it Affect Salt Intake?

Mythri Shankar et al. Kidney Int Rep. .
No abstract available

PubMed Disclaimer

Figures

Figure 1
Figure 1
Healthy adults (blue) patients with chronic kidney disease (red). Recognition threshold to salt (left panels) and aversion to salt (right panels). Each panel shows the cumulative percentage of individuals responding to the specified salt concentrations. Data redrawn from Okuno-Ozeki et al.
See this image and copyright information in PMC

Comment on

  • Aversion to a High Salt Taste is Disturbed in Patients With CKD.
    Okuno-Ozeki N, Kohama Y, Taguchi H, Kawate Y, Umehara M, Minamida A, Yamauchi-Sawada H, Sunahara Y, Matoba Y, Nakamura I, Nakai K, Nakata T, Kirita Y, Taniguchi T, Tamagaki K, Hirao T, Matoba S, Kusaba T. Okuno-Ozeki N, et al. Kidney Int Rep. 2024 Feb 16;9(5):1254-1264. doi: 10.1016/j.ekir.2024.02.1393. eCollection 2024 May. Kidney Int Rep. 2024. PMID: 38707820 Free PMC article.

References

    1. Tarumo K., Gordon M.D. Molecular and cellular mechanisms of Salt taste. Annu Rev Physiol. 2023;85:25–45. doi: 10.1146/annurev-physiol-031522-075853. - DOI - PubMed
    1. Zhang Y., Pool A.H., Wang T., et al. Parallel neural pathways control sodium consumption and taste valence. Cell. 2023;186:5751–5765. doi: 10.1016/j.cell.2023.10.020. - DOI - PMC - PubMed
    1. Bigiani A., Does E. C work as a taste receptor? Nutrients. 2020;12:1195. doi: 10.3390/nu12041195. - DOI - PMC - PubMed
    1. Kashlan O.B., Wang X.-P., Sheng S., Kleyman T.R. Epithelial Na Channels function as extracellular sensors. Comp Physiol. 2024;14:5407–5447. doi: 10.1002/cphy.c230015. - DOI
    1. Okuno-Ozeki N., Kohama Y., Taguchi H., et al. Aversion to a high salt taste is disturbed in patients with CKD. Kidney Int Rep. 2024;9:1254–1264. doi: 10.1016/j.ekir.2024.02.1393. - DOI - PMC - PubMed

LinkOut - more resources