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Editorial
. 2024 May 7;9(7):1947-1950.
doi: 10.1016/j.ekir.2024.04.071. eCollection 2024 Jul.

Kidney Disease in the Caribbean-APOL1 Risk Alleles and Emerging Environmental Stressors

Affiliations
Editorial

Kidney Disease in the Caribbean-APOL1 Risk Alleles and Emerging Environmental Stressors

Joseph Myrie et al. Kidney Int Rep. .
No abstract available

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Figures

Figure 1
Figure 1
Direction of the transatlantic slave trade from West Africa to the Caribbean. Map Volume and direction transatlantic slave trade. Although the Caribbean had an existing native population, large numbers of enslaved persons from West Africa were disembarked in the early part of the 18th century; larger than any other country in North America. In total, about 2.6 million enslaved persons were brought to the British Caribbean (about 23% of the transatlantic slave trade).

References

    1. Laurence K.O., Cuesta Jorge Ibarra. UNESCO; 2011. General history of the Caribbean, v. IV: The Long nineteenth century: nineteenth century transformations.
    1. Knight F.W. Oxford University Press; New York: 2012. The Caribbean: the Genesis of a Fragmented Nationalism.
    1. Bello A.K., McIsaac M., Okpechi I.G., et al. International society of nephrology global kidney health atlas: structures, organization, and services for the management of kidney failure in North America and the Caribbean. Kidney Int Suppl (2011) 2021;(11):e66–e76. doi: 10.1016/j.kisu.2021.01.001. - DOI - PMC - PubMed
    1. Nadkarni G.N., Gignoux C.R., Sorokin E.P., et al. Worldwide frequencies of APOL1 renal risk variants. N Engl J Med. 2018;379:2571–2572. doi: 10.1056/NEJMc1800748. - DOI - PMC - PubMed
    1. Egbuna O., Zimmerman B., Manos G., et al. Inaxaplin for proteinuric kidney disease in persons with two APOL1 variants. N Engl J Med. 2023;388:969–979. doi: 10.1056/NEJMoa2202396. - DOI - PubMed

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