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. 2024 Jul 31;47(1):374.
doi: 10.1007/s10143-024-02527-5.

Treatment of large intracranial aneurysms using the Woven EndoBridge (WEB): a propensity score-matched analysis

Basel Musmar #  1   2 Hamza Adel Salim #  1 Nimer Adeeb  3 Assala Aslan  1 Bahaa Aljeradat  1 Jose Danilo Bengzon Diestro  4 Rachel M McLellan  5 Oktay Algin  6 Sherief Ghozy  7 Mahmoud Dibas  1 Sovann V Lay  8 Adrien Guenego  9 Leonardo Renieri  10 Nicole M Cancelliere  4 Joseph Carnevale  11 Guillaume Saliou  12 Panagiotis Mastorakos  2 Kareem El Naamani  2 Eimad Shotar  13 Kevin Premat  13 Markus Möhlenbruch  14 Michael Kral  15 Justin E Vranic  5 Charlotte Chung  16 Mohamed M Salem  17 Ivan Lylyk  18 Paul M Foreman  19 Jay A Vachhani  19 Hamza Shaikh  20 Vedran Župančić  21 Muhammad U Hafeez  22 Joshua Catapano  23 Muhammad Waqas  24 Vincent M Tutino  24 Mohamed K Ibrahim  7 Marwa A Mohammed  7 M Ozgur Ozates  25 Giyas Ayberk  25 James D Rabinov  5 Yifan Ren  26 Clemens M Schirmer  27 Mariangela Piano  28 Anna L Kühn  29 Caterina Michelozzi  30 Stéphanie Elens  10 Robert M Starke  31 Ameer Hassan  32 Mark Ogilvie  33 Anh Nguyen  34 Jesse Jones  33 Waleed Brinjikji  7 Marie T Nawka  35 Marios Psychogios  34 Christian Ulfert  14 Julian Spears  4 Brian T Jankowitz  17 Jan-Karl Burkhardt  17 Ricardo A Domingo  36 Thien Huynh  36 Juan Carlos Martinez-Gutierrez  37 Muhammed Amir Essibayi  38 Sunil A Sheth  37 Gary Spiegel  37 Rabih Tawk  36 Boris Lubicz  10 Pietro Panni  30 Ajit S Puri  29 Guglielmo Pero  28 Erez Nossek  16 Eytan Raz  16 Monika Killer-Oberfalzer  15 Christoph J Griessenauer  15 Hamed Asadi  16 Adnan Siddiqui  24 Allan Brook  38 David Altschul  38 Andrew F Ducruet  23 Felipe C Albuquerque  23 Robert W Regenhardt  5 Christopher J Stapleton  5 Peter Kan  22 Vladimir Kalousek  21 Pedro Lylyk  18 Srikanth Boddu  12 Jared Knopman  12 Mohammad A Aziz-Sultan  6 Stavropoula I Tjoumakaris  2 Frédéric Clarençon  13 Nicola Limbucci  11 Hugo H Cuellar-Saenz  1 Pascal M Jabbour  2 Vitor Mendes Pereira  5 Aman B Patel  5 Adam A Dmytriw  5
Affiliations

Treatment of large intracranial aneurysms using the Woven EndoBridge (WEB): a propensity score-matched analysis

Basel Musmar et al. Neurosurg Rev. .

Abstract

The Woven EndoBridge (WEB) device is primarily used for treating wide-neck intracranial bifurcation aneurysms under 10 mm. Limited data exists on its efficacy for large aneurysms. We aim to assess angiographic and clinical outcomes of the WEB device in treating large versus small aneurysms. We conducted a retrospective review of the WorldWide WEB Consortium database, from 2011 to 2022, across 30 academic institutions globally. Propensity score matching (PSM) was employed to compare small and large aneurysms on baseline characteristics. A total of 898 patients were included. There was no significant difference observed in clinical presentations, smoking status, pretreatment mRS, presence of multiple aneurysms, bifurcation location, or prior treatment between the two groups. After PSM, 302 matched pairs showed significantly lower last follow-up adequate occlusion rates (81% vs 90%, p = 0.006) and higher retreatment rates (12% vs 3.6%, p < 0.001) in the large aneurysm group. These findings may inform treatment decisions and patient counseling. Future studies are needed to further explore this area.

Keywords: Aneurysms; Intracranial; Treatment; WEB; Woven EndoBridge.

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Conflict of interest statement

The authors declare no competing interests.

Figures

Fig. 1
Fig. 1
Flowchart shows the inclusion for patients and aneurysms in this study
Fig. 2
Fig. 2
ROC curve analyses for aneurysmal size in relation to retreatment rate

References

    1. Chalouhi N, Tjoumakaris S, Gonzalez LF et al (2014) Coiling of large and giant aneurysms: complications and long-term results of 334 cases. AJNR Am J Neuroradiol 35(3):546–552. 10.3174/ajnr.A3696 - PMC - PubMed
    1. UCAS Japan Investigators, Morita A, Kirino T et al (2012) The natural course of unruptured cerebral aneurysms in a Japanese cohort. N Engl J Med. 366(26):2474–2482. 10.1056/NEJMoa1113260 - PubMed
    1. Sundt TM, Piepgras DG (1979) Surgical approach to giant intracranial aneurysms. Operative experience with 80 cases. J Neurosurg. 51(6):731–742. 10.3171/jns.1979.51.6.0731 - PubMed
    1. Kalani MYS, Zabramski JM, Hu YC, Spetzler RF (2013) Extracranial-intracranial bypass and vessel occlusion for the treatment of unclippable giant middle cerebral artery aneurysms. Neurosurgery 72(3):428–435; discussion 435–436. 10.1227/NEU.0b013e3182804381 - PubMed
    1. van Rooij WJ, Sluzewski M (2009) Endovascular treatment of large and giant aneurysms. AJNR Am J Neuroradiol 30(1):12–18. 10.3174/ajnr.A1267 - PMC - PubMed

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