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Review
. 2024 Aug 6;84(6):561-580.
doi: 10.1016/j.jacc.2024.05.048.

Pericardial Diseases and Best Practices for Pericardiectomy: JACC State-of-the-Art Review

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Free article
Review

Pericardial Diseases and Best Practices for Pericardiectomy: JACC State-of-the-Art Review

Mohamed Al-Kazaz et al. J Am Coll Cardiol. .
Free article

Abstract

Remarkable advances have occurred in the understanding of the pathophysiology of pericardial diseases and the role of multimodality imaging in this field. Medical therapy and surgical options for pericardial diseases have also evolved substantially. Pericardiectomy is indicated for chronic or irreversible constrictive pericarditis, refractory recurrent pericarditis despite optimal medical therapy, or partial agenesis of the pericardium with a complication (eg, herniation). A multidisciplinary evaluation before pericardiectomy is essential for optimal patient outcomes. Overall, given the good outcomes reported, radical pericardiectomy on cardiopulmonary bypass, if feasible, is the preferred approach. Due to patient complexity, as well as the technical aspects of the surgery, pericardiectomy should be performed at high-volume centers that have the required expertise. The current review highlights the essential features of this multidisciplinary approach from diagnosis to recovery in patients undergoing pericardiectomy.

Keywords: constrictive pericarditis; pericardial disease; pericardiectomy; recurrent pericarditis; risk stratification.

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Conflict of interest statement

Funding Support and Author Disclosures Dr Al-Kazaz has received research grant and speaking honoraria from Kiniksa pharmaceuticals. Dr Klein has received research grant and scientific advisory board honoraria from Kiniksa pharmaceuticals and Cardiol Therapeutics. Dr Cremer has served on scientific advisory boards for Kiniksa pharmaceuticals and Cardiol Therapeutics. Dr Tong has received consulting and speaking honoraria from Abbott and Abiomed. Dr Johnston has received consulting honoraria from Edwards Lifesciences, Medtronic, Terumo Aortic, and Artivion. All other authors have reported that they have no relationships relevant to the contents of this paper to disclose.

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