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. 2024 Aug 6;84(6):592-594.
doi: 10.1016/j.jacc.2024.05.046.

Plasma Proteomic Biomarkers of Aortic Stenosis: A Mendelian Randomization Study

Ta-Yu Yang  1 , Aeron M Small  2 , Line Dufresne  3 , Gina M Peloso  4 , Pradeep Natarajan  5 , James C Engert  6 , George Thanassoulis  7
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Free article

Plasma Proteomic Biomarkers of Aortic Stenosis: A Mendelian Randomization Study

Ta-Yu Yang et al. J Am Coll Cardiol. .
Free article
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Conflict of interest statement

Funding Support and Author Disclosures This study has been funded by the Canadian Institutes of Health Research (CIHR), the Heart and Stroke Foundation of Canada (HSFC), the National Institutes of Health, and the U.S. Department of Veterans Affairs. Dr Natarajan has received research grants from Allelica, Apple, Amgen, Boston Scientific, Genentech/Roche, and Novartis; has received personal fees from Allelica, Apple, AstraZeneca, Blackstone Life Sciences, Eli Lilly & Co, Foresite Labs, Genentech/Roche, GV, HeartFlow, Magnet Biomedicine, and Novartis; has held scientific advisory board membership for Esperion Therapeutics, Preciseli, and TenSixteen Bio; has served as a scientific cofounder of TenSixteen Bio; has held equity in MyOme, Preciseli, and TenSixteen Bio; and has disclosed spousal employment at Vertex Pharmaceuticals, all unrelated to the present work. Dr Thanassoulis has received consulting fees from Ionis Pharmaceuticals; and has participated in advisory boards for Amgen, Sanofi, Novartis, HLS Therapeutics, and Silence. All other authors have reported that they have no relationships relevant to the contents of this paper to disclose.

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