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. 1985 Dec;38(12):1366-73.
doi: 10.1136/jcp.38.12.1366.

Biopsy findings in cases of rejection of liver allograft

S G Hubscher, D Clements, E Elias, P McMaster

Biopsy findings in cases of rejection of liver allograft

S G Hubscher et al. J Clin Pathol. 1985 Dec.

Abstract

Features of rejection were found in 21 needle biopsies obtained from seven patients after liver transplantation. Wedge biopsies taken peroperatively were used as a baseline for comparison. Rejection was diagnosed by excluding other known causes of graft dysfunction using appropriate methods. In cases in which these criteria were fulfilled a consistent picture of rejection was seen, and this was useful in clinical management. Two features constantly present in cases of acute rejection were: a dense mixed portal inflammatory infiltrate; and polymorphonuclear infiltration of biliary epithelium.

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