Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2024 Jul 26;16(7):402-411.
doi: 10.4330/wjc.v16.i7.402.

Rates, predictors, and causes of readmission after transcatheter aortic valve replacement in patients with chronic kidney disease

Taha Teaima  1 , Gianfranco Bittar Carlini  1 , Rohan A Gajjar  1 , Imran Aziz  1 , Sami J Shoura  1 , Abdul-Rahim Shilbayeh  1 , Naim Battikh  1 , Tareq Alyousef  2
Affiliations

Rates, predictors, and causes of readmission after transcatheter aortic valve replacement in patients with chronic kidney disease

Taha Teaima et al. World J Cardiol. .

Abstract

Background: Transcatheter aortic valve replacement (TAVR) is a revolutionary procedure for severe aortic stenosis. The coexistence of chronic kidney disease (CKD) and TAVR introduces a challenge that significantly impacts patient outcomes.

Aim: To define readmission rates, predictors, and causes after TAVR procedure in CKD stage 1-4 patients.

Methods: We used the national readmission database 2018 and 2020 to look into readmission rates, causes and predictors after TAVR procedure in patients with CKD stage 1-4.

Results: Out of 24758 who underwent TAVR and had CKD, 7892 (32.4%) patients were readmitted within 90 days, and had higher adjusted odds of being females (adjusted odds ratio: 1.17, 95%CI: 1.02-1.31, P = 0.02) with longer length of hospital stay > 6 days, and more comorbidities including but not limited to diabetes mellitus, anemia, and congestive heart failure (CHF).

Conclusion: Most common causes of readmission included CHF (18.0%), sepsis, and complete atrioventricular block. Controlling readmission predictors with very close follow-up is warranted to prevent such high rate of readmission.

Keywords: Chronic kidney disease; Predictors; Rates; Readmission; Transcatheter aortic valve replacement.

PubMed Disclaimer

Conflict of interest statement

Conflict-of-interest statement: We have no financial relationships to disclose.

Figures

Figure 1
Figure 1
Flow chart of Readmission rates after transcatheter aortic valve replacement in chronic kidney disease stage 1-4 patient. TAVR: Transcatheter aortic valve replacement; CKD: Chronic kidney disease.
Figure 2
Figure 2
Most common causes of readmission.
Figure 3
Figure 3
Forrest plot for predictors of readmission when adjusted for patient demographics, comorbidities, and hospital characteristics.
See this image and copyright information in PMC

Similar articles

See all similar articles

References

    1. Siemieniuk RA, Agoritsas T, Manja V, Devji T, Chang Y, Bala MM, Thabane L, Guyatt GH. Transcatheter versus surgical aortic valve replacement in patients with severe aortic stenosis at low and intermediate risk: systematic review and meta-analysis. BMJ. 2016;354:i5130. - PMC - PubMed
    1. Thourani VH, Kodali S, Makkar RR, Herrmann HC, Williams M, Babaliaros V, Smalling R, Lim S, Malaisrie SC, Kapadia S, Szeto WY, Greason KL, Kereiakes D, Ailawadi G, Whisenant BK, Devireddy C, Leipsic J, Hahn RT, Pibarot P, Weissman NJ, Jaber WA, Cohen DJ, Suri R, Tuzcu EM, Svensson LG, Webb JG, Moses JW, Mack MJ, Miller DC, Smith CR, Alu MC, Parvataneni R, D'Agostino RB Jr, Leon MB. Transcatheter aortic valve replacement versus surgical valve replacement in intermediate-risk patients: a propensity score analysis. Lancet. 2016;387:2218–2225. - PubMed
    1. Writing Committee Members. Otto CM, Nishimura RA, Bonow RO, Carabello BA, Erwin JP 3rd, Gentile F, Jneid H, Krieger EV, Mack M, McLeod C, O'Gara PT, Rigolin VH, Sundt TM 3rd, Thompson A, Toly C. 2020 ACC/AHA Guideline for the Management of Patients With Valvular Heart Disease: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. J Am Coll Cardiol. 2021;77:e25–e197. - PubMed
    1. GBD Chronic Kidney Disease Collaboration. Global, regional, and national burden of chronic kidney disease, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet. 2020;395:709–733. - PMC - PubMed
    1. Vavilis G, Bäck M, Occhino G, Trevisan M, Bellocco R, Evans M, Lindholm B, Szummer K, Carrero JJ. Kidney Dysfunction and the Risk of Developing Aortic Stenosis. J Am Coll Cardiol. 2019;73:305–314. - PubMed

LinkOut - more resources