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. 2024 Dec;29(12):1290-1291.
doi: 10.1016/j.tplants.2024.07.012. Epub 2024 Jul 31.

The BAHD and the bold: the mitochondria's role in alkaloid artistry

John C D'Auria  1 , Alisdair R Fernie  2
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Free article

The BAHD and the bold: the mitochondria's role in alkaloid artistry

John C D'Auria et al. Trends Plant Sci. 2024 Dec.
Free article

Abstract

In a recent study, Zeng et al. uncovered 3β-tigloyloxytropane synthase (TS) in Atropa belladonna, characterizing its mitochondrial localization and substrate specificity. The discovery of this enzyme opens up new bioengineering possibilities for tropane alkaloids (TAs), enhancing the potential for sustainable agriculture and expanding our knowledge of TA biosynthesis.

Keywords: Atropa belladonna; BAHD; acyltransferase; alkaloid; calystegine; tropane.

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Conflict of interest statement

Declaration of interests The authors declare no conflicts of interests.

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