Recommendations of the DNA Commission of the International Society for Forensic Genetics (ISFG) on short tandem repeat sequence nomenclature

Katherine B Gettings¹, Martin Bodner², Lisa A Borsuk³, Jonathan L King⁴, David Ballard⁵, Walther Parson⁶, Corina C G Benschop⁷, Claus Børsting⁸, Bruce Budowle⁹, John M Butler³, Kristiaan J van der Gaag⁷, Peter Gill¹⁰, Leonor Gusmão¹¹, Douglas R Hares¹², Jerry Hoogenboom⁷, Jodi Irwin¹², Lourdes Prieto¹³, Peter M Schneider¹⁴, Marielle Vennemann¹⁵, Christopher Phillips¹⁶

Affiliations

¹ National Institute of Standards and Technology, Gaithersburg, MD, USA. Electronic address: katherine.gettings@nist.gov.
² Institute of Legal Medicine, Medical University of Innsbruck, Innsbruck, Austria.
³ National Institute of Standards and Technology, Gaithersburg, MD, USA.
⁴ Center for Human Identification, University of North Texas Health Science Center, Fort Worth, TX, USA.
⁵ King's Forensics, Department of Analytical, Environmental and Forensic Sciences, King's College London, London, United Kingdom.
⁶ Institute of Legal Medicine, Medical University of Innsbruck, Innsbruck, Austria; Forensic Science Program, The Pennsylvania State University, University Park, PA, USA.
⁷ Division of Biological Traces, Netherlands Forensic Institute, The Hague, the Netherlands.
⁸ Section of Forensic Genetics, Department of Forensic Medicine, University of Copenhagen, Denmark.
⁹ Department of Forensic Medicine, University of Helsinki, Helsinki, Finland; Radford University Forensic Science Institute, Radford University, Radford, VA, USA.
¹⁰ Forensic Genetics Research Group, Oslo University Hospital, Oslo, Norway.
¹¹ DNA Diagnostic Laboratory, State University of Rio de Janeiro, Rio de Janeiro, Brazil.
¹² FBI Laboratory, Quantico, VA, USA.
¹³ Forensic Sciences Institute Luis Concheiro. University of Santiago de Compostela, Santiago de Compostela, Spain; Comisaría General de Policía Científica, Madrid, Spain.
¹⁴ Institute of Legal Medicine, University of Cologne, Cologne, Germany.
¹⁵ Institute of Legal Medicine, University of Münster, Münster, Germany.
¹⁶ Forensic Sciences Institute Luis Concheiro. University of Santiago de Compostela, Santiago de Compostela, Spain.

PMID: 39090852
DOI: 10.1016/j.fsigen.2023.102946

Free article

Recommendations of the DNA Commission of the International Society for Forensic Genetics (ISFG) on short tandem repeat sequence nomenclature

Katherine B Gettings et al. Forensic Sci Int Genet. 2024 Jan.

Free article

. 2024 Jan:68:102946.

doi: 10.1016/j.fsigen.2023.102946. Epub 2023 Oct 18.

Authors

Affiliations

¹ National Institute of Standards and Technology, Gaithersburg, MD, USA. Electronic address: katherine.gettings@nist.gov.
² Institute of Legal Medicine, Medical University of Innsbruck, Innsbruck, Austria.
³ National Institute of Standards and Technology, Gaithersburg, MD, USA.
⁴ Center for Human Identification, University of North Texas Health Science Center, Fort Worth, TX, USA.
⁵ King's Forensics, Department of Analytical, Environmental and Forensic Sciences, King's College London, London, United Kingdom.
⁶ Institute of Legal Medicine, Medical University of Innsbruck, Innsbruck, Austria; Forensic Science Program, The Pennsylvania State University, University Park, PA, USA.
⁷ Division of Biological Traces, Netherlands Forensic Institute, The Hague, the Netherlands.
⁸ Section of Forensic Genetics, Department of Forensic Medicine, University of Copenhagen, Denmark.
⁹ Department of Forensic Medicine, University of Helsinki, Helsinki, Finland; Radford University Forensic Science Institute, Radford University, Radford, VA, USA.
¹⁰ Forensic Genetics Research Group, Oslo University Hospital, Oslo, Norway.
¹¹ DNA Diagnostic Laboratory, State University of Rio de Janeiro, Rio de Janeiro, Brazil.
¹² FBI Laboratory, Quantico, VA, USA.
¹³ Forensic Sciences Institute Luis Concheiro. University of Santiago de Compostela, Santiago de Compostela, Spain; Comisaría General de Policía Científica, Madrid, Spain.
¹⁴ Institute of Legal Medicine, University of Cologne, Cologne, Germany.
¹⁵ Institute of Legal Medicine, University of Münster, Münster, Germany.
¹⁶ Forensic Sciences Institute Luis Concheiro. University of Santiago de Compostela, Santiago de Compostela, Spain.

PMID: 39090852
DOI: 10.1016/j.fsigen.2023.102946

Abstract

The DNA Commission of the International Society for Forensic Genetics (ISFG) has developed a set of nomenclature recommendations for short tandem repeat (STR) sequences. These recommendations follow the 2016 considerations of the DNA Commission of the ISFG, incorporating the knowledge gained through research and population studies in the intervening years. While maintaining a focus on backward compatibility with the CE data that currently populate national DNA databases, this report also looks to the future with the establishment of recommended minimum sequence reporting ranges to facilitate interlaboratory comparisons, automated solutions for sequence-based allele designations, a suite of resources to support bioinformatic development, guidance for characterizing new STR loci, and considerations for incorporating STR sequences and other new markers into investigative databases.

Keywords: DNA sequencing; Forensic genetics; Nomenclature; Quality control; Short tandem repeat.

Published by Elsevier B.V.

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Conflict of interest statement

Declaration of Competing Interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Bruce Budowle: Currently Consultant with Verogen.

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Recommendations of the DNA Commission of the International Society for Forensic Genetics (ISFG) on short tandem repeat sequence nomenclature

Affiliations

Recommendations of the DNA Commission of the International Society for Forensic Genetics (ISFG) on short tandem repeat sequence nomenclature

Authors

Affiliations

Abstract

Conflict of interest statement

MeSH terms

LinkOut - more resources

Full Text Sources