Advances in Neuroimaging Biomarkers and Scoring
- PMID: 39095101
- DOI: 10.1016/j.clp.2024.04.005
Advances in Neuroimaging Biomarkers and Scoring
Abstract
MRI of the brain is a critical tool in the diagnosis, evaluation, and management of neonatal encephalopathy (NE). More than simply a diagnostic and prognostic tool, MRI informs the biology, nature, and timing of the disease process resulting in NE, of which the largest single etiology is hypoxic-ischemic encephalopathy (HIE). Historically, 2 major patterns of injury were seen in HIE: a basal ganglia/thalamus predominant pattern and a watershed pattern of injury. The advent of therapeutic hypothermia for NE/HIE, alongside improvements in the application of imaging technology in newborn infants, has resulted in progressively more advanced MRI scoring systems.
Keywords: Biomarker; MRI score; Neonatal neuroimaging.
Copyright © 2024 Elsevier Inc. All rights reserved.
Conflict of interest statement
Disclosure The authors have nothing to disclose.
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