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Comparative Study
. 1985;7(6):377-85.

Hetero-organic thymus antigens

L V Beletskaya, E V Gnezditskaya
  • PMID: 3909541
Comparative Study

Hetero-organic thymus antigens

L V Beletskaya et al. Thymus. 1985.

Abstract

The use of sera containing antibodies to tissue-specific antigens of highly specialized organs (skeletal muscles, heart, skin, excretory glands) enabled us to detect, by immunofluorescence, cells capable of synthesizing analogous antigens (i.e. hetero-organic thymus antigens) in human and animal thymus. Detection of hetero-organic antigens in the thymus is the basis for the hypothesis that natural immunological tolerance to tissue self antigens is formed within the thymus in the course of T-lymphocyte maturation, with thymus antigens taking part in the process.

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