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Review
. 2024 Aug;47(4):102191.
doi: 10.1016/j.clae.2024.102191. Epub 2024 Jun 29.

BCLA CLEAR presbyopia: Management with scleral techniques, lens softening, pharmaceutical and nutritional therapies

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Free article
Review

BCLA CLEAR presbyopia: Management with scleral techniques, lens softening, pharmaceutical and nutritional therapies

Shehzad A Naroo et al. Cont Lens Anterior Eye. 2024 Aug.
Free article

Abstract

The aging eye undergoes the same progressive crosslinking which occurs throughout the body, resulting in increased rigidity of ocular connective tissues including the lens and the sclera which impact ocular functions. This offers the potential for a scleral treatment that is based on restoring normal biomechanical movements. Laser Scleral Microporation is a laser therapy that evaporates fractional areas of crosslinked tissues in the sclera, reducing ocular rigidity over critical anatomical zones of the accommodation apparatus, restoring the natural dynamic range of focus of the eye. Although controversial and challenged, an alternative theory for presbyopia is Schachar's theory that suggests a reduction in the space between the ciliary processes and the crystalline lens. Widening of this space with expansion bands has been shown to aid near vision in people with presbyopia, a technique that has been used in the past but seems to be obsolete now. The use of drugs has been used in the treatment of presbyopia, either to cause pupil miosis to increase depth of focus, or an alteration in refractive error (to induce myopia in one eye to create monovision). Drugs and laser ablation of the crystalline lens have been used with the aim of softening the hardened lens. Poor nutrition and excess exposure to ultraviolet light have been implicated in the onset of presbyopia. Dietary nutritional supplements, lifestyle changes have also been shown to improve accommodation and the question arises whether these could be harnessed in a treatment for presbyopia as well.

Keywords: Lens, miosis; Nutrition; Pharmaceutical; Presbyopia; Sclera.

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Conflict of interest statement

Declaration of competing interest Shehzad A. Naroo has received unrestricted grant funding from Lenstec, Teleon Surgical and Topcon Europe. Craig Woods is a paid consultant for Brien Holden Vision Institute and Zeiss Vision Care. Raquel Gil-Cazorla has received unrestricted grant funding from Lenstec. AnnMarie Hipsley, Edwin R. Price, Robert E. Ang, and Mitchell A. Jackson, are consultants for Ace Vision Group, Inc. James S. Wolffsohn has received grant funding from Alcon and Rayner, and is a paid consultant for Atia Vision, Bausch + Lomb and Alcon. Marianna Collazos, Frank Eperjesi and Michel Guillon have declared no financial interests.

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