Dr Lip has reported that he has served as a consultant and speaker for BMS/Pfizer, Boehringer Ingelheim, Daiichi-Sankyo, and Anthos. No fees were received personally. He is a National Institute for Health and Care Research Senior Investigator and co–Principal Investigator of the AFFIRMO project on multimorbidity in atrial fibrillation (grant agreement no. 899871), TARGET project on digital twins for personalized management of atrial fibrillation and stroke (grant agreement no. 101136244), and ARISTOTELES project on artificial intelligence for management of chronic long-term conditions (grant agreement no. 101080189), which are all funded by the European Union’s Horizon Europe Research & Innovation program. All other authors have reported that they have no relationships relevant to the contents of this paper to disclose.