Combination of PARP and DNA methylation inhibitors as a potential personalized therapy for SETD2-mutated clear-cell renal cancers
- PMID: 39100825
- PMCID: PMC11291424
- DOI: 10.21037/tau-24-20
Combination of PARP and DNA methylation inhibitors as a potential personalized therapy for SETD2-mutated clear-cell renal cancers
Keywords: DNA methylation; PARP inhibitors (PARPi); SETD2 mutation; renal cell carcinoma.
Conflict of interest statement
Conflicts of Interest: Both authors have completed the ICMJE uniform disclosure form (available at https://tau.amegroups.com/article/view/10.21037/tau-24-20/coif). The authors have no conflicts of interest to declare.
Comment on
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SETD2 Deficiency Confers Sensitivity to Dual Inhibition of DNA Methylation and PARP in Kidney Cancer.Cancer Res. 2023 Nov 15;83(22):3813-3826. doi: 10.1158/0008-5472.CAN-23-0401. Cancer Res. 2023. PMID: 37695044 Free PMC article.
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