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. 2024 Oct;116(4):899-901.
doi: 10.1002/cpt.3403. Epub 2024 Aug 5.

Pharmacogenomic Prescribing Guidelines: Are They Always Useful?

Magnus Ingelman-Sundberg  1
Affiliations

Pharmacogenomic Prescribing Guidelines: Are They Always Useful?

Magnus Ingelman-Sundberg. Clin Pharmacol Ther. 2024 Oct.
No abstract available

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References

    1. Ingelman‐Sundberg, M. & Pirmohamed, M. Precision medicine in cardiovascular therapeutics: evaluating the role of pharmacogenetic analysis prior to drug treatment. J. Intern. Med. 295, 583–598 (2024).
    1. CPIC® Guideline for Clopidogrel and CYP2C19 <https://cpicpgx.org/guidelines/guideline‐for‐clopidogrel‐and‐cyp2c19/>.
    1. Duarte, J.D. et al. Clinical Pharmacogenetics Implementation Consortium guideline for CYP2D6, ADRB1, ADRB2, ADRA2C, GRK4, and GRK5 genotypes and Beta‐blocker therapy. Clin. Pharmacol. Ther. 116, 939–947 (2024).
    1. Collett, S. et al. Metoprolol and CYP2D6: a retrospective cohort study evaluating genotype‐based outcomes. J Pers Med. 13, 416 (2023).
    1. Meloche, M. , Khazaka, M. , Kassem, I. , Barhdadi, A. , Dubé, M.P. & de Denus, S. CYP2D6 polymorphism and its impact on the clinical response to metoprolol: a systematic review and meta‐analysis. Br. J. Clin. Pharmacol. 86, 1015–1033 (2020).

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