Surrogate End Points in Trials-SPIRIT and CONSORT Extensions

Rod S Taylor^{1

2}, Anthony Muchai Manyara^{1

3}, Joseph S Ross^{4

5}, Oriana Ciani⁶

Affiliations

¹ Medical Research Council and Chief Scientist Office, Social and Public Health Sciences Unit, School of Health and Well Being, University of Glasgow, Glasgow, United Kingdom.
² Robertson Centre for Biostatistics, School of Health and Well Being, University of Glasgow, Glasgow, United Kingdom.
³ Global Health and Ageing Research Unit, Bristol Medical School, University of Bristol, Bristol, United Kingdom.
⁴ Department of Health Policy and Management, Yale School of Public Health, and Section of General Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut.
⁵ Deputy Editor, JAMA.
⁶ Centre for Research on Health and Social Care Management, SDA Bocconi School of Management, Milan, Italy.

Rod S Taylor et al. JAMA. 2024.

. 2024 Aug 5.

doi: 10.1001/jama.2024.15219. Online ahead of print.

Rod S Taylor^{1

2}, Anthony Muchai Manyara^{1

3}, Joseph S Ross^{4

5}, Oriana Ciani⁶

¹ Medical Research Council and Chief Scientist Office, Social and Public Health Sciences Unit, School of Health and Well Being, University of Glasgow, Glasgow, United Kingdom.
² Robertson Centre for Biostatistics, School of Health and Well Being, University of Glasgow, Glasgow, United Kingdom.
³ Global Health and Ageing Research Unit, Bristol Medical School, University of Bristol, Bristol, United Kingdom.
⁴ Department of Health Policy and Management, Yale School of Public Health, and Section of General Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut.
⁵ Deputy Editor, JAMA.
⁶ Centre for Research on Health and Social Care Management, SDA Bocconi School of Management, Milan, Italy.

No abstract available

Comment in

CONSORT 2025 Statement: Updated Guideline for Reporting Randomized Trials.
Hopewell S, Chan AW, Collins GS, Hróbjartsson A, Moher D, Schulz KF, Tunn R, Aggarwal R, Berkwits M, Berlin JA, Bhandari N, Butcher NJ, Campbell MK, Chidebe RCW, Elbourne D, Farmer A, Fergusson DA, Golub RM, Goodman SN, Hoffmann TC, Ioannidis JPA, Kahan BC, Knowles RL, Lamb SE, Lewis S, Loder E, Offringa M, Ravaud P, Richards DP, Rockhold FW, Schriger DL, Siegfried NL, Staniszewska S, Taylor RS, Thabane L, Torgerson D, Vohra S, White IR, Boutron I. Hopewell S, et al. JAMA. 2025 Jun 10;333(22):1998-2005. doi: 10.1001/jama.2025.4347. JAMA. 2025. PMID: 40228499