Differences in major adverse cardiovascular events of metabolic dysfunction-associated steatotic liver disease by race and ethnicity: Letter to the editor on "Differences in liver and mortality outcomes of non-alcoholic fatty liver disease by race and ethnicity: A longitudinal real-world study"

Hui-Chin Chang^{1

2

3}, Wen-Chieh Liao^{4

5}, Yi-Jen Fang^{4

6}, Shiu-Jau Chen^{7

8}, Shuo-Yan Gau^{9

10

11}

Affiliations

¹ Evidence-based Medicine Center, Chung Shan Medical University Hospital, Taichung, Taiwan.
² Library, Chung Shan Medical University Hospital, Taichung, Taiwan.
³ School of Medicine, Chung Shan Medical University, Taichung, Taiwan.
⁴ Department of Post-Baccalaureate Medicine, College of Medicine, National Chung Hsing University, Taichung, Taiwan.
⁵ Doctoral Program in Tissue Engineering and Regenerative Medicine, College of Medicine, National Chung Hsing University, Taichung, Taiwan.
⁶ Digestive Disease Center, Show Chwan Memorial Hospital, Changhua, Taiwan.
⁷ Department of Neurosurgery, Mackay Memorial Hospital, Taipei, Taiwan.
⁸ Department of Medicine, Mackay Medical College, New Taipei City, Taiwan.
⁹ Department and Graduate Institute of Business Administration, National Taiwan University, Taipei, Taiwan.
¹⁰ Department of Pharmacology, Chung Shan Medical University, Taichung, Taiwan.
¹¹ Department of Orthopedics Department, Chi-Mei Medical Center, Tainan, Taiwan.

PMID: 39104001
PMCID: PMC11540368
DOI: 10.3350/cmh.2024.0565

Differences in major adverse cardiovascular events of metabolic dysfunction-associated steatotic liver disease by race and ethnicity: Letter to the editor on "Differences in liver and mortality outcomes of non-alcoholic fatty liver disease by race and ethnicity: A longitudinal real-world study"

Hui-Chin Chang et al. Clin Mol Hepatol. 2024 Oct.

. 2024 Oct;30(4):978-981.

doi: 10.3350/cmh.2024.0565. Epub 2024 Aug 5.

Authors

Hui-Chin Chang^{1

2

3}, Wen-Chieh Liao^{4

5}, Yi-Jen Fang^{4

6}, Shiu-Jau Chen^{7

8}, Shuo-Yan Gau^{9

10

11}

Affiliations

¹ Evidence-based Medicine Center, Chung Shan Medical University Hospital, Taichung, Taiwan.
² Library, Chung Shan Medical University Hospital, Taichung, Taiwan.
³ School of Medicine, Chung Shan Medical University, Taichung, Taiwan.
⁴ Department of Post-Baccalaureate Medicine, College of Medicine, National Chung Hsing University, Taichung, Taiwan.
⁵ Doctoral Program in Tissue Engineering and Regenerative Medicine, College of Medicine, National Chung Hsing University, Taichung, Taiwan.
⁶ Digestive Disease Center, Show Chwan Memorial Hospital, Changhua, Taiwan.
⁷ Department of Neurosurgery, Mackay Memorial Hospital, Taipei, Taiwan.
⁸ Department of Medicine, Mackay Medical College, New Taipei City, Taiwan.
⁹ Department and Graduate Institute of Business Administration, National Taiwan University, Taipei, Taiwan.
¹⁰ Department of Pharmacology, Chung Shan Medical University, Taichung, Taiwan.
¹¹ Department of Orthopedics Department, Chi-Mei Medical Center, Tainan, Taiwan.

PMID: 39104001
PMCID: PMC11540368
DOI: 10.3350/cmh.2024.0565

No abstract available

Keywords: Cohort; Electronic medical records; MACE; MASLD; Race disparity.

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Conflict of interest statement

Conflicts of Interest

The authors have no conflicts to disclose.

Figures

**Figure 1.**
Risk of MACE in MASLD patients with different races. Propensity score matching was reperformed in each analysis. All analysis was followed from 3 months after index date to 15 years after index date if not specifically stated. Matching model 1: matching covariates include age, sex, BMI; Matching model 2: matching covariates include age, sex, BMI, socioeconomic status, substance abuse. Matching model 3: matching covariates include age, sex, BMI, socioeconomic status, substance abuse, NSAIDs use. MACE, major adverse cardiovascular events; CI, confidence interval; BMI, body mass index.

See this image and copyright information in PMC

Comment on

Differences in liver and mortality outcomes of non-alcoholic fatty liver disease by race and ethnicity: A longitudinal real-world study.
Nguyen VH, Le I, Ha A, Le RH, Rouillard NA, Fong A, Gudapati S, Park JE, Maeda M, Barnett S, Cheung R, Nguyen MH. Nguyen VH, et al. Clin Mol Hepatol. 2023 Oct;29(4):1002-1012. doi: 10.3350/cmh.2023.0205. Epub 2023 Sep 11. Clin Mol Hepatol. 2023. PMID: 37691484 Free PMC article.

Cited by

Comparisons of Post-Load Glucose at Different Time Points for Identifying High Risks of MASLD Progression.
Teng L, Luo L, Sun Y, Wang W, Dong Z, Cao X, Ye J, Zhong B. Teng L, et al. Nutrients. 2024 Dec 31;17(1):152. doi: 10.3390/nu17010152. Nutrients. 2024. PMID: 39796589 Free PMC article.
Small intestinal bacterial overgrowth and metabolic dysfunction-associated steatotic liver disease.
Wang Z, Tan W, Huang J, Li Q, Wang J, Su H, Guo C, Liu H. Wang Z, et al. Front Nutr. 2024 Dec 17;11:1502151. doi: 10.3389/fnut.2024.1502151. eCollection 2024. Front Nutr. 2024. PMID: 39742106 Free PMC article.

References

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1. Shang Y, Widman L, Hagström H. Nonalcoholic fatty liver disease and risk of dementia: A Population-based cohort study. Neurology. 2022;99:e574–e582. - PMC - PubMed
1. Desai R, Alvi AT, Vasavada A, Pulakurthi YS, Patel B, Mohammed AS, et al. Sex and racial disparities in non-alcoholic fatty liver disease-related cardiovascular events: National inpatient sample analysis (2019) World J Cardiol. 2024;16:137–148. - PMC - PubMed

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Differences in major adverse cardiovascular events of metabolic dysfunction-associated steatotic liver disease by race and ethnicity: Letter to the editor on "Differences in liver and mortality outcomes of non-alcoholic fatty liver disease by race and ethnicity: A longitudinal real-world study"

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Differences in major adverse cardiovascular events of metabolic dysfunction-associated steatotic liver disease by race and ethnicity: Letter to the editor on "Differences in liver and mortality outcomes of non-alcoholic fatty liver disease by race and ethnicity: A longitudinal real-world study"

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