Penetration of isavuconazole into the epithelial lining fluid of patients with pulmonary fungal infections. Comment on: 'Pharmacokinetics of isavuconazole at different target sites in healthy volunteers after single and multiple intravenous infusions'

Alexis Maillard^{1

2}, Léo Froelicher Bournaud³, Jean Pastre⁴, Benjamin Planquette⁴, Perrine Parize², Fanny Lanternier^{2

5}, Camille Rasmussen¹, Camille Chenevier-Gobeaux⁶, Cherifa Cheurfa⁷, Sihem Benaboud^{3

8}, Caroline Charlier^{1

9

10

11}, Etienne Canouï¹

Affiliations

¹ Paris Centre University Cochin Hospital, Infectious Diseases Stewardship Team, AP-HP, Paris, France.
² Department of Infectious Diseases and Tropical Medicine, Necker-Enfants Malades University Hospital, AP-HP, Paris, France.
³ Clinical Pharmacology Department, Paris Centre University Cochin Hospital, AP-HP, Paris, France.
⁴ Hôpital Européen Georges Pompidou, Service de Pneumologie et Soins Intensifs, AP-HP, Paris, France.
⁵ Mycology Department, Institut Pasteur, Université Paris Cité, National Reference Center for Invasive Mycoses and Antifungals, Mycology Translational Research Group, Paris, France.
⁶ Paris Centre University Cochin Hospital, Biochemistry Laboratory, AP-HP, Paris, France.
⁷ Intensive Care Department, Paris Centre University Cochin Hospital, AP-HP, Paris, France.
⁸ EA7323, Evaluation des Thérapeutiques et Pharmacologie Périnatale et Pédiatrique, Université Paris Cité, Paris, France.
⁹ Département de maladies infectieuses, Université de Paris Cité, Paris, France.
¹⁰ Institut Pasteur, French National Reference Center and WHO Collaborating Center Listeria, Paris, France.
¹¹ Institut Pasteur, Biology of Infection Unit, Inserm U1117, Paris, France.

Comment

Alexis Maillard et al. J Antimicrob Chemother. 2024.

. 2024 Sep 3;79(9):2403-2405.

doi: 10.1093/jac/dkae258.

¹ Paris Centre University Cochin Hospital, Infectious Diseases Stewardship Team, AP-HP, Paris, France.
² Department of Infectious Diseases and Tropical Medicine, Necker-Enfants Malades University Hospital, AP-HP, Paris, France.
³ Clinical Pharmacology Department, Paris Centre University Cochin Hospital, AP-HP, Paris, France.
⁴ Hôpital Européen Georges Pompidou, Service de Pneumologie et Soins Intensifs, AP-HP, Paris, France.
⁵ Mycology Department, Institut Pasteur, Université Paris Cité, National Reference Center for Invasive Mycoses and Antifungals, Mycology Translational Research Group, Paris, France.
⁶ Paris Centre University Cochin Hospital, Biochemistry Laboratory, AP-HP, Paris, France.
⁷ Intensive Care Department, Paris Centre University Cochin Hospital, AP-HP, Paris, France.
⁸ EA7323, Evaluation des Thérapeutiques et Pharmacologie Périnatale et Pédiatrique, Université Paris Cité, Paris, France.
⁹ Département de maladies infectieuses, Université de Paris Cité, Paris, France.
¹⁰ Institut Pasteur, French National Reference Center and WHO Collaborating Center Listeria, Paris, France.
¹¹ Institut Pasteur, Biology of Infection Unit, Inserm U1117, Paris, France.

No abstract available

Comment on

Pharmacokinetics of isavuconazole at different target sites in healthy volunteers after single and multiple intravenous infusions.
Bergmann F, Wölfl-Duchek M, Jorda A, Al Jalali V, Leutzendorff A, Sanz-Codina M, Gompelmann D, Trimmel K, Weber M, Eberl S, Van Os W, Minichmayr IK, Reiter B, Stimpfl T, Idzko M, Zeitlinger M. Bergmann F, et al. J Antimicrob Chemother. 2024 May 2;79(5):1169-1175. doi: 10.1093/jac/dkae088. J Antimicrob Chemother. 2024. PMID: 38546795 Free PMC article.