Update on APPEAL, an International Randomized Controlled Trial Evaluating Ciprofloxacin Versus Placebo in Patients Undergoing Shockwave Lithotripsy for Urolithiasis

Collaborators, Affiliations

Affiliations

¹ Faculty of Medicine, University of Helsinki, Helsinki, Finland; Department of Urology, University of Helsinki and University Hospital Helsinki, Helsinki, Finland; Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Canada; Department of Surgery, South Karelian Central Hospital, Lappeenranta, Finland. Electronic address: kari.tikkinen@helsinki.fi.
² Department of Urology, University of Helsinki and University Hospital Helsinki, Helsinki, Finland.
³ Faculty of Medicine, University of Helsinki, Helsinki, Finland.
⁴ Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Canada; Division of Urology, Department of Surgery, University of Toronto, Toronto, Canada.
⁵ Department of Urology, Tabriz University of Medical Sciences, Tabriz, Iran; Research Center for Evidence-Based Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
⁶ Urology Section, Surgery Department, Hazm Mebaireek General Hospital, Hamad Medical Corporation, Doha, Qatar; Faculty of Medicine, Qatar University, Doha, Qatar.
⁷ Division of Urology, Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, Canada.
⁸ Department of Urology, University Hospital Basel, Basel, Switzerland.
⁹ Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Canada; Department of Oncology, McMaster University, Hamilton, Canada.
¹⁰ Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Canada; Department of Medicine, McMaster University, Hamilton, Canada.
¹¹ Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Canada; Division of Urology, Department of Surgery, McMaster University, Hamilton, Canada; Department of Surgery, Woodstock Hospital, Woodstock, Canada.

PMID: 39112135
DOI: 10.1016/j.euf.2024.07.011

Update on APPEAL, an International Randomized Controlled Trial Evaluating Ciprofloxacin Versus Placebo in Patients Undergoing Shockwave Lithotripsy for Urolithiasis

Kari A O Tikkinen et al. Eur Urol Focus. 2024 Sep.

. 2024 Sep;10(5):697-699.

doi: 10.1016/j.euf.2024.07.011. Epub 2024 Aug 6.

Affiliations

¹ Faculty of Medicine, University of Helsinki, Helsinki, Finland; Department of Urology, University of Helsinki and University Hospital Helsinki, Helsinki, Finland; Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Canada; Department of Surgery, South Karelian Central Hospital, Lappeenranta, Finland. Electronic address: kari.tikkinen@helsinki.fi.
² Department of Urology, University of Helsinki and University Hospital Helsinki, Helsinki, Finland.
³ Faculty of Medicine, University of Helsinki, Helsinki, Finland.
⁴ Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Canada; Division of Urology, Department of Surgery, University of Toronto, Toronto, Canada.
⁵ Department of Urology, Tabriz University of Medical Sciences, Tabriz, Iran; Research Center for Evidence-Based Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
⁶ Urology Section, Surgery Department, Hazm Mebaireek General Hospital, Hamad Medical Corporation, Doha, Qatar; Faculty of Medicine, Qatar University, Doha, Qatar.
⁷ Division of Urology, Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, Canada.
⁸ Department of Urology, University Hospital Basel, Basel, Switzerland.
⁹ Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Canada; Department of Oncology, McMaster University, Hamilton, Canada.
¹⁰ Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Canada; Department of Medicine, McMaster University, Hamilton, Canada.
¹¹ Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Canada; Division of Urology, Department of Surgery, McMaster University, Hamilton, Canada; Department of Surgery, Woodstock Hospital, Woodstock, Canada.

PMID: 39112135
DOI: 10.1016/j.euf.2024.07.011

Abstract

The blinded APPEAL trial is assessing the effectiveness of antimicrobial prophylaxis in preventing infections after shockwave lithotripsy for urinary stones. This large, pragmatic, international trial will provide trustworthy evidence to inform guidelines and influence global practices.

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Update on APPEAL, an International Randomized Controlled Trial Evaluating Ciprofloxacin Versus Placebo in Patients Undergoing Shockwave Lithotripsy for Urolithiasis

Collaborators

Affiliations

Update on APPEAL, an International Randomized Controlled Trial Evaluating Ciprofloxacin Versus Placebo in Patients Undergoing Shockwave Lithotripsy for Urolithiasis

Authors

Collaborators

Affiliations

Abstract

Publication types

MeSH terms

Substances

LinkOut - more resources

Full Text Sources