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Case Reports
. 2024 May-Jun;34(3):270-271.
doi: 10.4103/ijn.ijn_308_23. Epub 2024 Jan 18.

Renal Mucormycosis with Disseminated Lytic Bony Lesions

Vignesh Subramani  1 , Jasmine Sethi  1 , Vaishnavi Venkatasubramanian  1 , Parthraj Shenoy  2 , Chiterlekha Kundal  3 , Rajinder Kumar  4 , Nandita Kakkar  1
Affiliations
Case Reports

Renal Mucormycosis with Disseminated Lytic Bony Lesions

Vignesh Subramani et al. Indian J Nephrol. 2024 May-Jun.

Abstract

Renal Mucormycosis is a lethal opportunistic infection with extensive tissue invasion leading to infarction. We report a diabetic lady with disseminated fungal pyelonephritis presenting with extensive lytic bony lesions mimicking malignancy. Prompt initiation of antifungal therapy and surgical debridement is the key to successful management. A clinician should have a high index of suspicion for Mucormycosis in a patient with non-resolving pyelonephritis and prolonged fever.

Keywords: Mucormycosis; fungal; lytic bones; pyelonephritis; renal.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1:
Figure 1:
(a) FDG PET avid lytic skeletal lesions involving the sacrum, pelvic bones, and vertebrae. (b) Bilateral kidneys showing increasing FDG uptake in bilateral renal cortices with FDG-avid perinephric stranding. (c) Biopsy from sacral lesion showing extensive areas of necrosis with numerous broad foldable aseptate hyphae (black arrow) conforming to the morphology of Mucorales (hematoxylin and eosin stain, magnification 40×).
See this image and copyright information in PMC

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