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Review
. 2024 Jul 24:12:1439265.
doi: 10.3389/fped.2024.1439265. eCollection 2024.

Strategies for the prevention of bronchopulmonary dysplasia

Gianluca Dini  1 , Sara Ceccarelli  1 , Federica Celi  1
Affiliations
Review

Strategies for the prevention of bronchopulmonary dysplasia

Gianluca Dini et al. Front Pediatr. .

Abstract

Bronchopulmonary dysplasia (BPD) is a common morbidity affecting preterm infants and is associated with substantial long-term disabilities. The pathogenesis of BPD is multifactorial, and the clinical phenotype is variable. Extensive research has improved the current understanding of the factors contributing to BPD pathogenesis. However, effectively preventing and managing BPD remains a challenge. This review aims to provide an overview of the current evidence regarding the prevention of BPD in preterm infants, offering practical insights for clinicians.

Keywords: bronchopulmonary dysplasia; lung disease; neonatal care; postnatal corticosteroids; preterm infants.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
Definitions of BPD over time. BPD, bronchopulmonary dysplasia; CPAP, continuous positive airway pressure; DOL, day of life; FiO2, fraction of inspired oxygen; GA, gestational age; IMV, invasive mechanical ventilation; LPM, liters per minute; NC, nasal cannula; NIPPV, nasal intermittent positive pressure ventilation; PMA, postmenstrual age; RA, room air.
Figure 2
Figure 2
Chest radiograph of an infant with bronchopulmonary dysplasia.
See this image and copyright information in PMC

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