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Comparative Study
. 1979 Aug;38(2):216-8.
doi: 10.1128/aem.38.2.216-218.1979.

Bile acid inhibition of Clostridium botulinum

C M Huhtanen
Comparative Study

Bile acid inhibition of Clostridium botulinum

C M Huhtanen. Appl Environ Microbiol. 1979 Aug.

Abstract

Bile acids and their glycine and taurine conjugates were tested in vitro for inhibition of Clostridium botulinum types A and B. Cholic acid inhibited most strains at 2 mg/ml, whereas chenodeoxycholic acid inhibited all strains at 0.4 mg/ml. Deoxycholic acid inhibited one strain at 0.08 mg/ml and other strains at 0.4 and 2 mg/ml. Lithocholic acid inhibited all strains at 0.016 mg/ml. Glycine conjugates also showed considerable inhibition of some strains, whereas taurine conjugates were inactive.

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References

    1. J Clin Endocrinol Metab. 1965 May;25:678-85 - PubMed
    1. Lancet. 1976 Oct 30;2(7992):934-6 - PubMed
    1. J Infect Dis. 1977 May;135(5):850-4 - PubMed
    1. J Nutr. 1978 Aug;108(8):1289-96 - PubMed
    1. Lancet. 1966 Jul 2;2(7453):12-5 - PubMed

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