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Comment
. 2024 Aug 1;7(8):e2425600.
doi: 10.1001/jamanetworkopen.2024.25600.

Antiseizure Drugs and Pharmacogenetics-Is There Signal in the Noise?

David J Gagnon  1   2
Affiliations
Comment

Antiseizure Drugs and Pharmacogenetics-Is There Signal in the Noise?

David J Gagnon. JAMA Netw Open. .
No abstract available

PubMed Disclaimer

Conflict of interest statement

Dr. Gagnon has no real or perceived financial conflict of interest.

Comment on

References

    1. Brodie MJ. Antiepileptic drug therapy the story so far. Seizure. 2010;19(10):650–55. - PubMed
    1. Patsalos PN, Berry DJ, Bourgeois BFD, et al. Antiepileptic drugs--best practice guidelines for therapeutic drug monitoring: a position paper by the subcommission on therapeutic drug monitoring, ILAE Commission on Therapeutic Strategies. Epilepsia. 2008;49(7):1239–76. - PubMed
    1. Nebert DW, Russell DW. Clinical importance of the cytochromes P450. Lancet. 2002;360:1155–62. - PubMed
    1. Milosavljevic F, Manojlovic M, Matkovic L et al. Associations between pharmacogenetic biomarkers and plasma concentrations of antiepileptic drugs: a asysteamtic review and meta-analysis. JAMA Netw Open. 2024. (in press). - PMC - PubMed
    1. Zhou Y, Ingelman-Sunberg M, Lauschke VM. Worldwide distribution of cytochrome P450 alleles: A meta-analysis of population-scale sequencing projects. Clin Pharmacol Ther. 2017;102(4):688–700. - PMC - PubMed

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