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. 1985 Nov;28(5):700-2.
doi: 10.1128/AAC.28.5.700.

Elimination of plasmids by new 4-quinolones

J Weisser, B Wiedemann

Elimination of plasmids by new 4-quinolones

J Weisser et al. Antimicrob Agents Chemother. 1985 Nov.

Abstract

Nalidixic acid and six of the new 4-quinolones eliminated F'lac and various native R plasmids from Escherichia coli at one half or one quarter the MIC. Four of eight plasmids tested were cured by all derivatives, with frequencies from 10 to 98%. Quinolones did not eliminate all plasmids that were cured by novobiocin, and vice versa.

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References

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