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Comparative Study
. 1985 Dec;50(6):1509-11.
doi: 10.1128/aem.50.6.1509-1511.1985.

Studies on the sensitivity and specificity of the Limulus amebocyte lysate test and rabbit pyrogen assays

M J Devleeschouwer, M F Cornil, J Dony
Comparative Study

Studies on the sensitivity and specificity of the Limulus amebocyte lysate test and rabbit pyrogen assays

M J Devleeschouwer et al. Appl Environ Microbiol. 1985 Dec.

Abstract

The sensitivity and specificity of the Limulus amebocyte lysate test and rabbit pyrogen assay were studied by means of artificially contaminated parenterals. Various gram-negative and gram-positive bacterial strains were used as was one strain of the yeast Candida albicans. The numbers of organisms needed to elicit positive responses in distilled water and normal saline were recorded and compared. The sensitivity and specificity of the Limulus amebocyte lysate assay for the detection of bacterial endotoxin from gram-negative bacteria were demonstrated. Variable results were recorded with gram-positive bacteria and Candida albicans.

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References

    1. Bull Parenter Drug Assoc. 1977 May-Jun;31(3):127-33 - PubMed
    1. Proc Soc Exp Biol Med. 1971 May;137(1):334-40 - PubMed
    1. J Dent Res. 1977 Dec;56(12):1500 - PubMed
    1. Appl Microbiol. 1973 Oct;26(4):521-4 - PubMed
    1. Appl Environ Microbiol. 1980 Dec;40(6):1148-51 - PubMed

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