Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2024 May-Jun;69(3):269-272.
doi: 10.4103/ijd.ijd_420_22. Epub 2024 Jun 26.

Cutaneous Pseudolymphoma after COVID-19 Vaccine Injection

Affiliations

Cutaneous Pseudolymphoma after COVID-19 Vaccine Injection

Júlia Verdaguer-Faja et al. Indian J Dermatol. 2024 May-Jun.
No abstract available

PubMed Disclaimer

Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
Clinical and dermoscopic findings. (a). Physical examination: a reddish, elastic to touch and well-demarcated nodule, with a rounded and regular outline. (b). Dermoscopic evaluation: multiple non-focused, non-fine vessels on a pinkish erythematous background, with no other specific findings
Figure 2
Figure 2
(a) A benign nodular lymphoid proliferation extending from the superficial to the deep dermis with a top-heavy distribution, and a Grenz zone. (H and E, 2x). (b) Reactive germinal centre formation (H and E, 10x) with (c) small and mature lymphocytes, without atypia. (H and E,40x)
Figure 3
Figure 3
Immunohistochemistry reveals a polymorphous infiltrate with a mixture of B and T cells, highlighted by CD20 (a) and CD3 (b) stains. Germinal centres have a high proliferative index (c), highlighted by Ki67

References

    1. Català A, Muñoz-Santos C, Galván-Casas C, Roncero Riesco M, Revilla Nebreda D, Solá-Truyols A, et al. Cutaneous reactions after SARS-CoV-2 vaccination: A cross-sectional Spanish nationwide study of 405 cases. Br J Dermatol. 2022;186:142–52. - PMC - PubMed
    1. Ramos Pinheiro R, Duarte B, João A, Lencastre A. Cutaneous pseudolymphoma following quadrivalent human papillomavirus vaccination-a rare adverse event. J Dtsch Dermatol Ges. 2018;16:465–7. - PubMed
    1. Cerroni L, Borroni RG, Massone C, Chott A, Kerl H. Cutaneous B-cell Pseudolymphoma at the Site of Vaccination. Am J Dermatopathol. 2007;29:538–42. - PubMed
    1. Mintoff D, Scerri L, Betts A. SARS-CoV-2 mRNA vaccine injection site pseudolymphoma. J Eur Acad Dermatol Venereol. 2022;36:e20–2. - PMC - PubMed
    1. Pfizer, Inc. Fact sheet for recipients and caregivers about Pfizer-BioNTech COVID-19 vaccine, bivalent which has emergency use authorization (EUA) to prevent coronavirus disease 2019 (COVID-19) 2023. [Last accessed on 2023 Jun 30]. pp. 1–9. Available from:https://www.fda.gov/media/167212/download .

LinkOut - more resources