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Case Reports
. 2023 Jul 17;2(7):943-945.
doi: 10.1016/j.gastha.2023.06.013. eCollection 2023.

Duodenal-Type Follicular Lymphoma

Afra Abdulla Juma  1 , Faisal Abubaker  1 , Omar Sharif  1 , Eman Aljufairi  1
Affiliations
Case Reports

Duodenal-Type Follicular Lymphoma

Afra Abdulla Juma et al. Gastro Hep Adv. .

Abstract

This case report presents the clinical findings, diagnostic evaluation, and treatment options for a 71-year-old female patient with a medical history of hypertension, dyslipidemia, and recurrent urinary tract infections. The patient presented with chronic abdominal pain as the sole symptom. Despite normal laboratory investigations, esophagogastroduodenoscopy and ileocolonoscopy were performed. Biopsies were obtained from the duodenum and histopathological analysis confirmed a diagnosis of duodenal-type follicular lymphoma. This rare condition typically presents with minimal clinical symptoms and has a favorable prognosis. Treatment options for duodenal-type follicular lymphoma include a watch-and-wait strategy, rituximab monotherapy, and radiotherapy.

Keywords: Case Report; Duodenal-type; Esophagogastroduodenoscopy; Follicular Lymphoma.

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Figures

Figure 1
Figure 1
Upper endoscopy showing whitish duodenal spots in D2.
Figure 2
Figure 2
Duodenal biopsy: showing atypical lymphoid follicles.
Figure 3
Figure 3
The follicles lack mantle zone and tangible-body macrophages (H&E x 200).
Figure 4
Figure 4
(A–D) The follicles are positive for CD20, bcl-2, and bcl-6, while negative for CD3.
See this image and copyright information in PMC

References

    1. Marks E., Shi Y. Duodenal-type follicular lymphoma: a clinicopathologic review. Arch Pathol Lab Med. 2018;142(4):542–547. - PubMed
    1. Duffles Amarante G., Collins G., Rocha V. What do we know about duodenal-type follicular lymphoma? From pathological definition to treatment options. Br J Haematol. 2020;188(6):831–837. - PubMed

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