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Editorial
. 2024 Aug 1;1(8):335-337.
doi: 10.5588/ijtldopen.24.0336. eCollection 2024 Aug.

Rethinking latent TB? Think again

R E Chaisson  1 , P C Hopewell  2
Affiliations
Editorial

Rethinking latent TB? Think again

R E Chaisson et al. IJTLD Open. .
No abstract available

Keywords: HIV; TB infection; TBI; interferon-gamma release assay; tuberculin skin testing.

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Figures

Figure 1.
Figure 1.
Age-specific incidence rates of TB in the United States in 1972. The dotted line shows rates per 100,000, with increasing incidence in older individuals. The solid lines show the incidence rates in each age cohort over the previous 20 years, demonstrating sharp declines in incidence as the cohort ages. The data support the hypothesis that, while incidence declines with age, the higher prevalence of latent infection in older cohorts results in a higher age-specific incidence (reprinted from Ref. #7 with permission from Oxford University Press).
Figure 2.
Figure 2.
Global estimated age-specific incidence rates of TB per 100,000 people in 2022, demonstrating rising rates of disease associated with aging (data from).
See this image and copyright information in PMC

References

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    1. Chaisson RE, Nachega JB. Tuberculosis. In: Oxford Textbook of Medicine. Oxford, UK: Oxford University Press, 2020.
    1. Comstock GW, Livesay VT, Woolpert SF. The prognosis of a positive tuberculin reaction in childhood and adolescence. Am J Epidemiol. 1974;99(2):131–138. - PubMed

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