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Review
. 2024 Aug 7:11:20499361241267124.
doi: 10.1177/20499361241267124. eCollection 2024 Jan-Dec.

Acute drug-use-related native tricuspid valve infective endocarditis: a non-surgical disease

Sami El-Dalati  1 , Talal Alnabelsi  2 , John Gurley  2 , Kelli Cremeans  3 , Hassan Reda  4 , Tessa London-Bounds  4 , Erinn Ogburn  4 , Michael Sekela  4
Affiliations
Review

Acute drug-use-related native tricuspid valve infective endocarditis: a non-surgical disease

Sami El-Dalati et al. Ther Adv Infect Dis. .

Abstract

As a result of the ongoing opioid epidemic, physicians have encountered increasing rates of drug-use-related native tricuspid valve infective endocarditis (DU-TVIE), a complex multi-faceted disease that is best managed by interdisciplinary teams. Despite the large number of patients with DU-TVIE, there is little data to support the optimal treatment strategy with respect to medical and surgical therapy. The recent introduction of percutaneous mechanical aspiration of tricuspid valve vegetations has added another treatment modality that is also of uncertain benefit. Here we review the literature on the management of DU-TVIE and highlight the multi-step treatment approach developed by the multidisciplinary endocarditis team at the University of Kentucky.

Keywords: endocarditis; multidisciplinary teams; substance use disorder; tricuspid valve disease.

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Figures

Figure 1.
Figure 1.
Treatment pathway for patients with isolated native tricuspid valve endocarditis.
Figure 2.
Figure 2.
Front side of the University of Kentucky patient endocarditis prevention pocket card which outlines signs and symptoms of infective endocarditis and encourages patients to ask their medical provider to collect blood cultures before starting antibiotics for the listed symptoms.
Figure 3.
Figure 3.
Reverse side of the University of Kentucky patient endocarditis prevention pocket card which outlines indications and selection choice of antibiotic for prophylaxis as well as contact information for the infectious diseases clinic.
See this image and copyright information in PMC

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