Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2024 Aug 5:17:285-293.
doi: 10.2147/MDER.S468500. eCollection 2024.

Innovative Hematology Analysis Using Menstrual Blood

Affiliations

Innovative Hematology Analysis Using Menstrual Blood

Endah Wulandari et al. Med Devices (Auckl). .

Abstract

Purpose: The main aim of this study was to compare and analyze hematological profiles using menstrual blood, as an alternative to peripheral blood.

Patients and methods: This study used menstrual and peripheral blood samples from women who were menstruating. The design of this research is analytical observational.

Results: Menstrual blood can show an overall hematological profile similar to peripheral blood. Data shows the detection of blood component parameters, white blood cells and reticulocytes in MB with a range within and outside normal blood. Data on MB that show higher values (WBC, MCH, MCHC, PLT, RDW-CV, PDW, MPV, P-LCR, PCT, neutrophils, lymphocytes, monocytes, basophils, reticulocytes, LFR, Ret-He) and lower values lower (RBC, HGB, HCT, MVC, RDW-SD, Eosinophils, IRF, MFR, HFR) when compared with peripheral blood controls. The hematological profiles of Menstrual and peripheral blood showed significant differences (p < 0.01) for several parameters, while several other parameters did not show significant differences (p > 0.05) according to the Wilcoxon test.

Conclusion: All hematological profile parameters were detected in menstrual blood. The new concept that menstrual blood can be used as a supporting medium for hematological examinations opens up opportunities for developing independent hematological detection tools in productive women.

Keywords: RBC; WBC; hematological; menstrual blood; peripheral blood; reticulocyte.

PubMed Disclaimer

Conflict of interest statement

The authors report no conflicts of interest in this work.

References

    1. Wahyurin IS, Rahmah HA. Amount of menstrual blood and nutrient intake with hemoglobin level. KEMAS. 2021;17:31–36. doi:10.15294/kemas.v17i1.24540 - DOI
    1. Guterstam YC, Benedikt Ivarsson MA, Zimmer C, et al. The cytokine profile of menstrual blood. Acta Obstet Gynecol. 2021;100:339–346. doi:10.1111/aogs.13990 - DOI - PMC - PubMed
    1. Thiyagarajan DK, Hajira B, Rebecca J. Physiology Menstrual Cycle. StatPearls; 2022. - PubMed
    1. Hosseini S, Shokri F, Tokhmechy R, et al. Menstrual blood contains immune cells with inflammatory and anti-inflammatory properties. J Obstet Gynecol Res. 2015;41:1803–1812. - PubMed
    1. Yang H, Zhou B, Prinz M, Siegel D. Proteomic analysis of menstrual blood. Mol Cell Proteomics. 2012;11:1024–1035. doi:10.1074/mcp.M112.018390 - DOI - PMC - PubMed

LinkOut - more resources