Chimeric antigen receptor T-cell therapy associated hemophagocytic lymphohistiocytosis syndrome: clinical presentation, outcomes, and management
- PMID: 39134524
- PMCID: PMC11319601
- DOI: 10.1038/s41408-024-01119-2
Chimeric antigen receptor T-cell therapy associated hemophagocytic lymphohistiocytosis syndrome: clinical presentation, outcomes, and management
Conflict of interest statement
J.P. received research funding from Karyopharm. Y.W. received funding from Incyte, LOXO Oncology, Novartis, Genetech, and Morphosys; also had Incyte, LOXO Oncology, Eli Lilly, TG Therapeutics membership on advisory committee. Y.L. received research funding from Kite, Janssen, Celgene, Bluebird Bio, Merck, and Takeda; also received consulting fees from Janssen, Novartis, Celgene, Bluebird Bio, Juno, Legend, Sorrento, Gamida Cell, and Vineti. Also, LOXO Oncolgy, Incyte, Eli Lilly, and TG Therapeutics were taking part on an advisory committee. Stephen Ansell received from Bristol Myers Squibb, ADC Therapeutics, Seattle Genetics, Regeneron, Affimed, AITherapeutics, Pfizer, Trillium and Takeda.
References
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- Ahmed S. Haemophagocytic lymphohistiocytosis (HLH) in patients with large B-cell lymphoma treated with standard of care (SOC) axicabtagene ciloleucel (Axi-cel). American Society of Clinical Oncology: Journal of Clinical Oncology; 2020.
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