Lac-Phe (N-lactoyl-phenylalanine)
- PMID: 39137723
- PMCID: PMC11446501
- DOI: 10.1016/j.tem.2024.05.007
Lac-Phe (N-lactoyl-phenylalanine)
Conflict of interest statement
Declaration of interests The authors have no interests to declare
References
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- Jansen RS, Addie R, Merkx R, Fish A, Mahakena S, Bleijerveld OB, Altelaar M, IJlst L, Wanders RJ, Borst P, et al. (2015). N -lactoyl-amino acids are ubiquitous metabolites that originate from CNDP2-mediated reverse proteolysis of lactate and amino acids. Proc. Natl. Acad. Sci. U.S.A. 112, 6601–6606. 10.1073/pnas.1424638112. - DOI - PMC - PubMed
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- Sharma R, Reinstadler B, Engelstad K, Skinner OS, Stackowitz E, Haller RG, Clish CB, Pierce K, Walker MA, Fryer R, et al. (2021). Circulating markers of NADH-reductive stress correlate with mitochondrial disease severity. Journal of Clinical Investigation 131, e136055. 10.1172/JCI136055. - DOI - PMC - PubMed
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- Hoene M, Zhao X, Machann J, Birkenfeld A, Heni M, Peter A, Niess A, Moller A, Lehmann R, Xu G, et al. (2022). Exercise-Induced N-Lactoylphenylalanine Predicts Adipose Tissue Loss during Endurance Training in Overweight and Obese Humans. Metabolites 13, 15. 10.3390/metabo13010015. - DOI - PMC - PubMed
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