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Review
. 2024 Apr 23;12(8):5271-5284.
doi: 10.1002/fsn3.4183. eCollection 2024 Aug.

Bioactive peptides of marine organisms: Roles in the reduction and control of cardiovascular diseases

Jia Du  1   2 , Miao Xiao  2 , Naomi Sudo  2 , Qinghua Liu  2   3
Affiliations
Review

Bioactive peptides of marine organisms: Roles in the reduction and control of cardiovascular diseases

Jia Du et al. Food Sci Nutr. .

Abstract

Cardiovascular diseases (CVDs) affect the quality of life or are fatal in the worst cases, resulting in a significant economic and social burden. Therefore, there is an urgent need to invent functional products or drugs for improving patient health and alleviating and controlling these diseases. Marine bioactive peptides reduce and control CVDs. Many of the predisposing factors triggering CVDs can be alleviated by consuming functional foods containing marine biopeptides. Therefore, improving CVD incidence through the use of effective biopeptide foods from marine sources has attracted increasing interest and attention. This review reports information on bioactive peptides derived from various marine organisms, focusing on the process of the separation, purification, and identification of biological peptides, biological characteristics, and functional food for promoting cardiovascular health. Increasing evidence shows that the bioactivity and safety of marine peptides significantly impact their storage, purification, and processing. It is feasible to develop further strategies involving functional foods to treat CVDs through effective safety testing methods. Future work should focus on producing high-quality marine peptides and applying them in the food and drug industry.

Keywords: anticoagulant activity; antihypertensive activity; bioactive peptides; cardiovascular diseases; functional food; marine organisms.

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Conflict of interest statement

The authors declare that they do not have any conflict of interest.

Figures

FIGURE 1
FIGURE 1
Extraction, processing and application of bioactive peptides from marine proteins.
FIGURE 2
FIGURE 2
Process for the production and security detection of peptides.
See this image and copyright information in PMC

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