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Review
. 2024 Aug 12;17(15):1747-1764.
doi: 10.1016/j.jcin.2024.04.050.

Position Statement on Cardiac Computed Tomography Following Left Atrial Appendage Occlusion

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Free article
Review

Position Statement on Cardiac Computed Tomography Following Left Atrial Appendage Occlusion

Kasper Korsholm et al. JACC Cardiovasc Interv. .
Free article

Abstract

Left atrial appendage occlusion (LAAO) is rapidly growing as valid stroke prevention therapy in atrial fibrillation. Cardiac imaging plays an instrumental role in preprocedural planning, procedural execution, and postprocedural follow-up. Recently, cardiac computed tomography (CCT) has made significant advancements, resulting in increasing use both preprocedurally and in outpatient follow-up. It provides a noninvasive, high-resolution alternative to the current standard, transesophageal echocardiography, and may display advantages in both the detection and characterization of device-specific complications, such as peridevice leak and device-related thrombosis. The implementation of CCT in the follow-up after LAAO has identified new findings such as hypoattenuated thickening on the atrial device surface and left atrial appendage contrast patency, which are not readily assessable on transesophageal echocardiography. Currently, there is a lack of standardization for acquisition and interpretation of images and consensus on definitions of essential findings on CCT in the postprocedural phase. This paper intends to provide a practical and standardized approach to both acquisition and interpretation of CCT after LAAO based on a comprehensive review of the literature and expert consensus among European and North American interventional and imaging specialists.

Keywords: cardiac computed tomography; device-related thrombosis; left atrial appendage closure; peridevice leak.

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Conflict of interest statement

Funding Support and Author Disclosures Dr Korsholm has received speaker honorarium from Abbott and Boston Scientific. Dr Saw has received unrestricted research grant support from AstraZeneca, Abbott, Boston Scientific, and Servier; has received speaker honorarium from AstraZeneca, Abbott, Boston Scientific, and Sunovion; and is a consultant/proctor for Boston Scientific, AstraZeneca, and Abbott. Dr Wang has received research grant support from Boston Scientific; and is a consultant for Edwards Lifesciences, Boston Scientific, and Materialise. Dr Berti is a proctor for Abbott and Edwards Lifesciences. Dr Galea has received speaker honorarium from Boston Scientific. Dr De Backer is a consultant for Abbott. Dr Räber has received research grants to the institution from Abbott Vascular, Biotronik, Boston Scientific, Heartflow, Sanofi, Regeneron, Medis Medical Imaging Systems, and Bangerter-Rhyner Stiftung; and has received speaker or consultation fees from Abbott Vascular, Amgen, AstraZeneca, Canon, Novo Nordisk, Medtronic, Occlutech, and Sanofi outside the submitted work. Dr Alkhouli is on the Advisory Board for Abbott and Boston Scientific. Dr Nielsen-Kudsk is a consultant for Boston Scientific; and is a consultant/proctor for Abbott. All other authors have reported that they have no relationships relevant to the contents of this paper to disclose.

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