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. 2024 Aug 14;25(1):301.
doi: 10.1186/s12875-024-02566-3.

General practitioners' perspectives on lifestyle interventions for cognitive preservation in dementia prevention

Josefine Kappe  1 , Felix Wittmann  2 , Melanie Luppa  2 , Maria Isabel Cardona  3 , Solveign Weise  4 , Stephan Fuchs  4 , Robert Philipp Kosilek  5 , Linda Sanftenberg  5 , Christian Brettschneider  6 , Juliane Döhring  7 , Catharina Escales  7 , David Czock  8 , Birgitt Wiese  9 , Jochen René Thyrian  3   10   11 , Wolfgang Hoffmann  3   10 , Thomas Frese  4 , Jochen Gensichen  5 , Hans-Helmut König  6 , Hanna Kaduszkiewicz #  7 , Steffi Gerlinde Riedel-Heller #  2
Affiliations

General practitioners' perspectives on lifestyle interventions for cognitive preservation in dementia prevention

Josefine Kappe et al. BMC Prim Care. .

Abstract

Background: General practitioners (GPs) play a crucial role in identifying cognitive impairment and dementia and providing post-diagnostic care. This study investigates (1) how promising GP consider lifestyle changes to maintain cognitive performance in general, (2) GP beliefs about the power of modifiable health and lifestyle factors to maintain cognitive performance, and (3) whether those beliefs vary by GP age.

Methods: As part of the AgeWell.de trial, GPs (n = 72) completed a process evaluation questionnaire assessing their perspectives on lifestyle changes to preserve cognitive performance in elderly patients. In greater detail, their perceived efficacy of established risk and protective factors was investigated using a 5-point Likert scale. Descriptive statistical analyses were performed for research question (1) and (2). Spearman´s rank correlations and ordinal logistic regressions were used to answer research question (3). All results were interpreted exploratively.

Results: GPs rated the overall chance of lifestyle changes maintaining cognitive performance quite neutral with a median score of 3.0 (IQR = 2.0). They rated the efficacy of all the modifiable health and lifestyle factors high, with increase in physical and social activity ((Mdn = 5.0, IQR = 1.0) receiving the highest ratings with the narrowest range. Spearman's rank correlation indicated a significant positive relationship between age and the belief in "Optimization of nutrition" for preventing cognitive decline and dementia (ρ = .255, p = .041). However, ordinal logistic regressions showed no significant relationships between age and GP ratings of lifestyle change efficacy.

Conclusion: These findings highlight the positive perception of GPs on the efficacy of modifiable health and lifestyle factors for preventing cognitive decline and dementia.

Trial registration: The AgeWell.de trial is registered in the German Clinical Trials Register (DRKS; trial identifier: DRKS00013555, Registration Date 07 December 2017).

Keywords: Alzheimer´s disease; Dementia; General practitioner; Prevention; Risk factor.

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Conflict of interest statement

The authors declare no competing interests.

Figures

Fig. 1
Fig. 1
GPs perceptions on the promise of modifiable health and lifestyle factors for preventing cognitive decline and dementia (n = 72)
See this image and copyright information in PMC

References

    1. Blotenberg I, Hoffmann W, Thyrian JR. Dementia in Germany: epidemiology and prevention potential. Dtsch Arztebl Int. 2023;120(27–28):470–6. 10.3238/arztebl.m2023.0100. 10.3238/arztebl.m2023.0100 - DOI - PMC - PubMed
    1. Röhr S, Luck T, Bickel H, et al. Mortality in incident dementia - results from the German study on aging, cognition, and dementia in primary care patients. Acta Psychiatr Scand. 2015;132(4):257–69. 10.1111/acps.12454. 10.1111/acps.12454 - DOI - PubMed
    1. World Health Organization (WHO). Global status report on the public health response to dementia. Geneva: World Health Organization; 2021. https://www.who.int/publications/i/item/9789240033245. Accessed 18 Mar 2024.
    1. Yiannopoulou KG, Papageorgiou SG. Current and future treatments in Alzheimer disease: an update. J Cent Nerv Syst Dis. 2020;12: 1179573520907397. 10.1177/1179573520907397. 10.1177/1179573520907397 - DOI - PMC - PubMed
    1. Deutsche Alzheimer Gesellschaft e.V. Deutsche Alzheimer Gesellschaft stellt neue Zahlen zur Demenz vor: Deutlich mehr Erkrankte unter 65 Jahren als bisher angenommen [German Alzheimer’s Society presents new figures on dementia: significantly more sufferers under 65 than previously assumed]. 2022. https://www.deutsche-alzheimer.de/artikel/deutsche-alzheimer-gesellschaf.... Accessed 13 Mar 2024.

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