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Review
. 2024 Jul 30;16(7):4794-4806.
doi: 10.21037/jtd-23-774. Epub 2024 Jul 26.

Chest wall resections for non-small cell lung cancer: a literature review

Luyu Huang #  1 , Feng Li #  2 , Jens Neudecker  1 , Aron Elsner  1 , Julia Strauchmann  1 , Tomasz Dziodzio  1 , Haiyu Zhou  3 , Jens Rueckert  1
Affiliations
Review

Chest wall resections for non-small cell lung cancer: a literature review

Luyu Huang et al. J Thorac Dis. .

Abstract

Background and objective: The development of early screening for lung cancer has led to improved overall survival in patients with non-small cell lung cancer (NSCLC). However, the management of NSCLC patients with resectable and potentially resectable chest wall invasion (CWI) requires attention. The purpose of this review is to summarize the role of surgery (chest wall resections) in NSCLC patients with CWI.

Methods: A literature search and review from three databases (PubMed, Embase, and ScienceDirect) comprised the last 39 years. This review was focused on the treatment of NSCLC patients with CWI, mainly including the preoperative evaluation, principles of treatment and strategic decision-making, surgical complications, and prognostic factors.

Key content and findings: Through the collection of relevant literature on NSCLC that invades the chest wall, this narrative review describes the actual role in clinical practice and future developments of chest wall resections. Preoperative treatment requires the multidisciplinary team (MDT) team to conduct accurate clinical staging of the patient and pay attention to the patient's lymph node status and rib invasion status. The successful implementation of chest wall resection and possible chest wall reconstruction requires refined individualized treatment based on the patient's clinical characteristics, supplemented by possible postoperative systemic treatment.

Conclusions: Surgery plays an important role in treating NSCLC patients with CWI, and a collaborative, experienced MDT is an essential component of the successful treatment of CWI with lung cancer. In the future, more high-quality clinical research is needed to focus on CWI patients so that patients can receive more effective treatment options and better clinical prognosis.

Keywords: Non-small cell lung cancer (NSCLC); chest wall reconstruction; chest wall resection; surgery; thoracic wall.

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Conflict of interest statement

Conflicts of Interest: All authors have completed the ICMJE uniform disclosure form (available at https://jtd.amegroups.com/article/view/10.21037/jtd-23-774/coif). The special series “Chest Wall Resections and Reconstructions” was commissioned by the editorial office without any funding or sponsorship. The authors have no other conflicts of interest to declare.

Figures

Figure 1
Figure 1
Display of different types of reconstruction materials.
See this image and copyright information in PMC

References

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