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. 2024 Aug 15;18(8):e0012364.
doi: 10.1371/journal.pntd.0012364. eCollection 2024 Aug.

A standardized clinical database for research in Chagas disease: The NHEPACHA network

Adriana González Martínez  1   2 , Irene Losada-Galván  3   4 , Juan Carlos Gabaldón-Figueira  3 , Nieves Martínez-Peinado  3   5 , Roberto Magalhães Saraiva  6 , Marisa Liliana Fernández  7 , Janine M Ramsey  8 , Oscar Noya-González  9   10   11 , Belkisyole Alarcón de Noya  10 , Alejandro Gabriel Schijman  12 , Soledad Berón  13 , Marcelo Abril  13 , Joaquim Gascón  3   14 , Sergio Sosa-Estani  15   16 , María Jesús Pinazo  15 , Julio Alonso-Padilla  3   14 , Alejandro Marcel Hasslocher-Moreno  6 ; NHEPACHA network (Nuevas Herramientas para el diagnóstico y la evaluación del paciente con enfermedad de Chagas)
Affiliations

A standardized clinical database for research in Chagas disease: The NHEPACHA network

Adriana González Martínez et al. PLoS Negl Trop Dis. .

Abstract

The NHEPACHA Iberoamerican Network, founded on the initiative of a group of researchers from Latin American countries and Spain, aims to establish a research framework for Chagas disease that encompasses diagnosis and treatment. For this purpose, the network has created a questionnaire to gather relevant data on epidemiological, clinical, diagnostic, and therapeutic aspects of the disease. This questionnaire was developed based on a consensus of expert members of the network, with the intention of collecting high-quality standardized data, which can be used interchangeably by the different research centers that make up the NHEPACHA network. Furthermore, the network intends to offer a clinical protocol that can be embraced by other researchers, facilitating comparability among published studies, as well as the development of therapeutic response and progression markers.

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Conflict of interest statement

The authors have declared that no competing interests exist.

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