T-Cell Responses to Treponema pallidum Proteins in Blood and Skin to Advance Syphilis Vaccine Design: Learning From Nature
- PMID: 39147388
- PMCID: PMC11326806
- DOI: 10.1093/infdis/jiae246
T-Cell Responses to Treponema pallidum Proteins in Blood and Skin to Advance Syphilis Vaccine Design: Learning From Nature
Keywords: immune response; syphilis; treponema pallidum; vaccine.
Conflict of interest statement
Potential conflicts of interest. All authors: No reported conflicts. All authors have submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Conflicts that the editors consider relevant to the content of the manuscript have been disclosed.
Comment on
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Treponema pallidum Periplasmic and Membrane Proteins Are Recognized by Circulating and Skin CD4+ T Cells.J Infect Dis. 2024 Aug 16;230(2):281-292. doi: 10.1093/infdis/jiae245. J Infect Dis. 2024. PMID: 38932740 Free PMC article.
References
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- Radolf JD, Tramont EC, Salazar JC. Syphilis (Treponema pallidum). In: Mandell GL, Dolin R, Blaser MJ, eds. Mandell, Douglas and Bennett's principles and practice of infectious diseases. 9th ed. Philadelphia: Churchill Livingtone Elsevier, 2019:2865–92.
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- Peeling RW, Mabey D, Chen XS, Garcia PJ. Syphilis. Lancet 2023; 402:336–46. - PubMed
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- Centers for Disease Control and Prevention . Sexually transmitted infections surveillance, 2022. https://www.cdc.gov/std/statistics/2022/overview.htm. Accessed May 2024.
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