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Case Reports
. 2024 Aug 15;12(8):e9262.
doi: 10.1002/ccr3.9262. eCollection 2024 Aug.

Small cell lung cancer associated small bowel obstruction, a diagnostic conundrum: A case report

Mohammad Ayoub  1 , Mohannad Natheef AbuHaweeleh  2 , Nabil Mahmood  3 , Colin Clelland  4 , Malak Mohammad Ayoub  5 , Harman Saman  1   2
Affiliations
Case Reports

Small cell lung cancer associated small bowel obstruction, a diagnostic conundrum: A case report

Mohammad Ayoub et al. Clin Case Rep. .

Abstract

Small cell lung cancer (SCLC), a neuroendocrine aggressive subtype of lung cancer, is associated with paraneoplastic disorders in about 9% of patients. In this report, we describe a middle-aged man who presented with chronic bowel obstruction caused by chronic intestinal pseudo-obstruction (CIPO) due to SCLC.

Keywords: SCLC; bowel obstruction; chronic intestinal pseudo‐obstruction; lung cancer; paraneoplastic.

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Conflict of interest statement

The authors declare that they have no conflicts of interest to disclose.

Figures

FIGURE 1
FIGURE 1
CT scan with contrast of abdomen and pelvis. (A) coronal view showing fecalization of the small bowel and dilated proximal segments (arrow), irregular wall thickening of the short segment distal ileum (arrowhead). (B) cross sectional view showing redemonstration of the irregular wall thickening of the short segment distal ileum with only partial narrowing of the lumen (arrow).
FIGURE 2
FIGURE 2
Axial T2 fat saturated image from the MR enterography study shows asymmetrical small bowel wall thickening (arrowhead) and adjacent mesenteric lymphadenopathy (arrow) with no significant mechanical cause for intestinal obstruction.
FIGURE 3
FIGURE 3
Coronal reformatted image of a contrast CT study of the chest shows a solid infiltrative right hilar soft tissue density mass invading the mediastinum (arrow).
FIGURE 4
FIGURE 4
EBUS‐FNA of mediastinal lymph node. (A) smear of small cell carcinoma cells admixed with small lymphocytes (Pap stain) at ×800 magnification. (B) cell block from the sample showing strong and extensive staining with Synaptophysin (immunohistochemical stain with diaminobenzidine end product) at ×400 magnification.
FIGURE 5
FIGURE 5
PET‐CT scan showing hot uptake in different organs. Top left: Right hilar mass. Top right: Left adrenal mass. Bottom left: Mesenteric lymph nodes. Bottom right: Bowel mass.
FIGURE 6
FIGURE 6
PET CT scan showing post‐chemotherapy metabolic resolution in different organs. Top left: Right hilar mass. Top right: Left adrenal mass. Bottom left: Mesenteric lymph nodes. Bottom right: Bowel mass.
See this image and copyright information in PMC

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