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. 2024 Aug 13:13:27536130241265669.
doi: 10.1177/27536130241265669. eCollection 2024 Jan-Dec.

Optimization of a mHealth Physical Activity Promotion Intervention With Mindful Awareness for Young Adult Cancer Survivors: Design and Methods of Opt2Move Full Factorial Trial

Jean Miki Reading  1 , Payton Solk  1 , Julia Starikovsky  1 , Kristina Hasanaj  1 , Shirlene D Wang  1 , Juned Siddique  1 , Stacy D Sanford  2   3 , John Salsman  4 , Bruriah Horowitz  2 , Hannah Freeman  1 , Jacqueline Alexander  1 , Christina Sauer  2 , Bonnie Spring  1 , David Victorson  2 , Siobhan M Phillips  1
Affiliations

Optimization of a mHealth Physical Activity Promotion Intervention With Mindful Awareness for Young Adult Cancer Survivors: Design and Methods of Opt2Move Full Factorial Trial

Jean Miki Reading et al. Glob Adv Integr Med Health. .

Abstract

Background: Opt2Move is a theory-guided moderate and vigorous physical activity (MVPA) promotion trial that uses multiphase optimization strategy (MOST) methodology to evaluate the individual and combined effects of four intervention components in a full factorial experiment among young adult cancer survivors (YACS; N = 304). All participants will receive the core mHealth MVPA intervention, which includes a Fitbit and standard self-monitoring Opt2Move smartphone application. YACS will be randomized to one of 16 conditions to receive between zero and four additional components each with two levels (yes v. no): E-Coach, buddy, general mindfulness, and MVPA-specific mindfulness.

Objective: The primary aim is to determine the individual and combined effects of the components on MVPA post-intervention (12-weeks) and at 24-week follow-up. The secondary aim is to examine how changes in MVPA are associated with patient-reported outcomes, light-intensity activity, sedentary time, and sleep duration and quality. Potential mediators and moderators of component effects will also be examined.

Results: Results will support the selection of a package of intervention components optimized to maximize MVPA to be tested in a randomized controlled trial.

Conclusion: Opt2Move represents the first systematic effort to use MOST to design an optimized, scalable mHealth MVPA intervention for YACS and will lead to an improved understanding of how to effectively change YACS' MVPA and ultimately, improve health and disease outcomes.

Keywords: cancer; health coaching; health promotion; mhealth; mindfulness; young adults.

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Conflict of interest statement

The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Figures

Figure 1.
Figure 1.
Opt2Move intervention mobile app home screen and component features.
Figure 2.
Figure 2.
Opt2Move conceptual model.
See this image and copyright information in PMC

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