Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2024 Aug 18;14(1):19125.
doi: 10.1038/s41598-024-70236-6.

Effect of texture and color enhancement imaging on the visibility of gastric tumors

Hiroaki Sakai #  1 , Naoto Iwai #  2   3 , Osamu Dohi  4 , Kohei Oka  1   4 , Takashi Okuda  1   4 , Toshifumi Tsuji  1 , Kengo Okabe  1   4 , Tomoya Ohara  1   4 , Mariko Kajiwara-Kubtota  1 , Hayato Fukui  1 , Junichi Sakagami  1 , Keizo Kagawa  1 , Ken Inoue  4 , Naohisa Yoshida  4 , Kazuhiko Uchiyama  4 , Tomohisa Takagi  4 , Hideyuki Konishi  4 , Yoshito Itoh  4
Affiliations

Effect of texture and color enhancement imaging on the visibility of gastric tumors

Hiroaki Sakai et al. Sci Rep. .

Abstract

Texture and color enhancement imaging (TXI) may improve the visibility of gastric tumors and allow their early detection. However, few reports have examined the utility of TXI. Between June 2021 and October 2022, 56 gastric tumors in 51 patients undergoing endoscopic submucosal dissection at Fukuchiyama City Hospital were evaluated preoperatively using conventional white light imaging (WLI), narrow-band imaging (NBI), and TXI modes 1 and 2. The color differences of the tumors and surrounding mucosae were evaluated using the CIE 1976 L*a*b color space, Additionally, the visibility scores were scaled. Of the 56 gastric tumors, 45 were early gastric cancers, and 11 were adenomas. Overall, the color difference in TXI mode 1 was considerably higher compared to WLI (16.36 ± 7.05 vs. 10.84 ± 4.05; p < 0.01). Moreover, the color difference in early gastric cancers was considerably higher in TXI mode 1 compared to WLI, whereas no significant difference was found in adenomas. The visibility score in TXI mode 1 was the highest, and it was significantly higher compared to WLI. Regarding adenomas, the visibility score in TXI mode 1 was also significantly higher compared to that in WLI. TXI may provide improved gastric tumor visibility.

Keywords: Adenoma; Early gastric cancer; Texture and color enhancement imaging; Visibility; White light imaging.

PubMed Disclaimer

Conflict of interest statement

The authors declare no competing interests.

Figures

Figure 1
Figure 1
Study flowchart. ESD, endoscopic submucosal dissection.
Figure 2
Figure 2
Representative images of gastric tumors before endoscopic submucosal dissection (ESD) obtained using white light imaging (WLI), narrow-band imaging (NBI), and texture and color enhancement imaging (TXI) modes 1 and 2. A straight line was drawn on the tumor image, and two areas (17 × 17 pixels) were plotted for each tumor and its surrounding mucosa on the line to calculate the color difference.
Figure 3
Figure 3
Representative images of gastric tumors and visibility scores. The visibility scores of narrow-band imaging (NBI) and texture and color enhancement imaging (TXI) modes 1 and 2 were compared with those white light imaging (WLI). The visibility scores were as follows: + 2 (remarkably improved), + 1 (improved), 0 (unchanged), − 1 (worsened), and − 2 (remarkably worsened).
See this image and copyright information in PMC

References

    1. Bray, F. et al. Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J. Clin.74, 229–263 (2024). 10.3322/caac.21834 - DOI - PubMed
    1. Suvakovic, Z. et al. Improving the detection rate of early gastric cancer requires more than open access gastroscopy: a five year study. Gut41, 308–313 (1997). 10.1136/gut.41.3.308 - DOI - PMC - PubMed
    1. Hosokawa, O. et al. Diagnosis of gastric cancer up to three years after negative upper gastrointestinal endoscopy. Endoscopy30, 669–674 (1998). 10.1055/s-2007-1001386 - DOI - PubMed
    1. Voutilainen, M. E. & Juhola, M. T. Evaluation of the diagnostic accuracy of gastroscopy to detect gastric tumours: Clinicopathological features and prognosis of patients with gastric cancer missed on endoscopy. Eur. J. Gastroenterol. Hepatol.17, 1345–1349 (2005). 10.1097/00042737-200512000-00013 - DOI - PubMed
    1. Vradelis, S., Maynard, N., Warren, B. F., Keshav, S. & Travis, S. P. Quality control in upper gastrointestinal endoscopy: Detection rates of gastric cancer in Oxford 2005–2008. Postgrad. Med. J.87, 335–339 (2011). 10.1136/pgmj.2010.101832 - DOI - PubMed

LinkOut - more resources