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. 1985 Oct;5(10):2874-7.
doi: 10.1128/mcb.5.10.2874-2877.1985.

Activation of c-myb expression by phytohemagglutinin stimulation in normal human T lymphocytes

G Torelli, L Selleri, A Donelli, S Ferrari, G Emilia, D Venturelli, L Moretti, U Torelli

Activation of c-myb expression by phytohemagglutinin stimulation in normal human T lymphocytes

G Torelli et al. Mol Cell Biol. 1985 Oct.

Abstract

The expression of c-myb in normal human T lymphocytes directly derived from a normal subject and not adapted to continuous growth in culture was found to be markedly increased after phytohemagglutinin stimulation. In the same cells, the expression of c-myc mRNA is a much earlier event compared with the appearance of c-myb mRNA, which takes place soon after that of histone H3 mRNA. The increase in c-myb expression was not due to a particular T-lymphocyte subset, as shown by in situ hybridization assays.

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