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. 2024 May 30;5(8):806-810.
doi: 10.1002/bco2.377. eCollection 2024 Aug.

Safety of urethral preservation using urethral frozen section analysis in radical cystectomy

Yuto Hattori  1 , Akihiko Nagoshi  1 , Tasuku Fujiwara  1 , Takanari Kambe  1 , Yuta Mine  1 , Hiroki Hagimoto  1 , Yohei Abe  1 , Daisuke Yamashita  2 , Naofumi Tsutsumi  1 , Noboru Shibasaki  1 , Toshinari Yamasaki  1 , Mutsushi Kawakita  1
Affiliations

Safety of urethral preservation using urethral frozen section analysis in radical cystectomy

Yuto Hattori et al. BJUI Compass. .

Erratum in

  • Erratum.
    [No authors listed] [No authors listed] BJUI Compass. 2024 Dec 30;5(12):1324-1329. doi: 10.1002/bco2.482. eCollection 2024 Dec. BJUI Compass. 2024. PMID: 39744071 Free PMC article.

Abstract

Background: The objective of this study is to assess whether urethral preservation can be performed safely using frozen section analysis (FSA) of the urethral stump on urethral recurrence after radical cystectomy.

Methods: Between June 2012 and July 2022, we investigated consecutive male patients who underwent urethral FSA during radical cystectomy for urothelial carcinoma. For FSA-abnormal cases, urethrectomy was performed, and for FSA-normal cases, the urethra was preserved. The diagnostic accuracy of FSA was assessed in comparison with the pathological findings of the permanent sections of the same tissue. Postoperatively, computed tomography and urinary cytology were performed as routine surveillance of recurrence.

Results: Of the 77 patients included in this study, three patients with abnormal FSA underwent concurrent urethrectomy. The negative predictive value of urethral FSA was 100%. With a median postoperative follow-up of 38 months (interquartile ranges 21-71), no urethral recurrence was observed.

Conclusions: FSA may be useful in determining the indication for urethrectomy.

Keywords: cystectomy; frozen sections; recurrence; urethra; urinary bladder neoplasms.

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Conflict of interest statement

The authors have no conflicts of interest to disclose.

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