Increasing associations of long-COVID with small-fiber neuropathy

doi:10.1097/j.pain.0000000000003260

. 2024 Sep 1;165(9):e93-e95.

doi: 10.1097/j.pain.0000000000003260. Epub 2024 May 3.

Increasing associations of long-COVID with small-fiber neuropathy

Anne Louise Oaklander^{1

2}

Affiliations

¹ Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States.
² Department of Pathology (Neuropathology), Massachusetts General Hospital, Boston, MA, United States.

PMID: 39159474
PMCID: PMC11343176 (available on 2025-09-01)
DOI: 10.1097/j.pain.0000000000003260

Increasing associations of long-COVID with small-fiber neuropathy

Anne Louise Oaklander. Pain. 2024.

. 2024 Sep 1;165(9):e93-e95.

doi: 10.1097/j.pain.0000000000003260. Epub 2024 May 3.

Author

Anne Louise Oaklander^{1

2}

Affiliations

¹ Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States.
² Department of Pathology (Neuropathology), Massachusetts General Hospital, Boston, MA, United States.

PMID: 39159474
PMCID: PMC11343176 (available on 2025-09-01)
DOI: 10.1097/j.pain.0000000000003260

No abstract available

PubMed Disclaimer

Conflict of interest statement

The author reports no Conflicts of Interest.

References

1. Abrams RMC, Simpson DM, Navis A, Jette N, Zhou L, Shin SC. Small fiber neuropathy associated with SARS-CoV-2 infection. Muscle Nerve 2022;65:440–43. - PMC - PubMed
1. Albrecht PJ, Hou Q, Argoff CE, Storey JR, Wymer JP, Rice FL. Excessive peptidergic sensory innervation of cutaneous arteriole-venule shunts (AVS) in the palmar glabrous skin of fibromyalgia patients: implications for widespread deep tissue pain and fatigue. Pain Med 2013;14:895–915. - PubMed
1. Boneparth A, Chen S, Horton DB, Moorthy LN, Farquhar I, Downs HM, Lee H, Oaklander AL. Epidermal neurite density in skin biopsies from patients with juvenile fibromyalgia. J Rheumatol 2021;48:575–78. - PMC - PubMed
1. Chan ACY, Wong HY, Chong YF, Lai PS, Teoh HL, Ng AYY, Hung JHM, Chan YC, Ng KWP, Vijayan J, Ong JJY, Chandra B, Tan CH, Rutt NH, Tan TM, Ismail NH, Wilder-Smith E, Schwarz H, Choi H, Sharma VK, Mak A Novel autoantibodies in idiopathic small fiber neuropathy. Ann Neurol 2022;91:66–77. - PMC - PubMed
1. Chiu IM, Heesters BA, Ghasemlou N, Von Hehn CA, Zhao F, Tran J, Wainger B, Strominger A, Muralidharan S, Horswill AR, Bubeck WJ, Hwang SW, Carroll MC, Woolf CJ. Bacteria activate sensory neurons that modulate pain and inflammation. Nature 2013;501:52–57. - PMC - PubMed

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[1] Abrams RMC, Simpson DM, Navis A, Jette N, Zhou L, Shin SC. Small fiber neuropathy associated with SARS-CoV-2 infection. Muscle Nerve 2022;65:440–43. - PMC - PubMed

[2] Abrams RMC, Simpson DM, Navis A, Jette N, Zhou L, Shin SC. Small fiber neuropathy associated with SARS-CoV-2 infection. Muscle Nerve 2022;65:440–43. - PMC - PubMed

[3] Albrecht PJ, Hou Q, Argoff CE, Storey JR, Wymer JP, Rice FL. Excessive peptidergic sensory innervation of cutaneous arteriole-venule shunts (AVS) in the palmar glabrous skin of fibromyalgia patients: implications for widespread deep tissue pain and fatigue. Pain Med 2013;14:895–915. - PubMed

[4] Albrecht PJ, Hou Q, Argoff CE, Storey JR, Wymer JP, Rice FL. Excessive peptidergic sensory innervation of cutaneous arteriole-venule shunts (AVS) in the palmar glabrous skin of fibromyalgia patients: implications for widespread deep tissue pain and fatigue. Pain Med 2013;14:895–915. - PubMed

[5] Boneparth A, Chen S, Horton DB, Moorthy LN, Farquhar I, Downs HM, Lee H, Oaklander AL. Epidermal neurite density in skin biopsies from patients with juvenile fibromyalgia. J Rheumatol 2021;48:575–78. - PMC - PubMed

[6] Boneparth A, Chen S, Horton DB, Moorthy LN, Farquhar I, Downs HM, Lee H, Oaklander AL. Epidermal neurite density in skin biopsies from patients with juvenile fibromyalgia. J Rheumatol 2021;48:575–78. - PMC - PubMed

[7] Chan ACY, Wong HY, Chong YF, Lai PS, Teoh HL, Ng AYY, Hung JHM, Chan YC, Ng KWP, Vijayan J, Ong JJY, Chandra B, Tan CH, Rutt NH, Tan TM, Ismail NH, Wilder-Smith E, Schwarz H, Choi H, Sharma VK, Mak A Novel autoantibodies in idiopathic small fiber neuropathy. Ann Neurol 2022;91:66–77. - PMC - PubMed

[8] Chan ACY, Wong HY, Chong YF, Lai PS, Teoh HL, Ng AYY, Hung JHM, Chan YC, Ng KWP, Vijayan J, Ong JJY, Chandra B, Tan CH, Rutt NH, Tan TM, Ismail NH, Wilder-Smith E, Schwarz H, Choi H, Sharma VK, Mak A Novel autoantibodies in idiopathic small fiber neuropathy. Ann Neurol 2022;91:66–77. - PMC - PubMed

[9] Chiu IM, Heesters BA, Ghasemlou N, Von Hehn CA, Zhao F, Tran J, Wainger B, Strominger A, Muralidharan S, Horswill AR, Bubeck WJ, Hwang SW, Carroll MC, Woolf CJ. Bacteria activate sensory neurons that modulate pain and inflammation. Nature 2013;501:52–57. - PMC - PubMed

[10] Chiu IM, Heesters BA, Ghasemlou N, Von Hehn CA, Zhao F, Tran J, Wainger B, Strominger A, Muralidharan S, Horswill AR, Bubeck WJ, Hwang SW, Carroll MC, Woolf CJ. Bacteria activate sensory neurons that modulate pain and inflammation. Nature 2013;501:52–57. - PMC - PubMed

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Increasing associations of long-COVID with small-fiber neuropathy

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Increasing associations of long-COVID with small-fiber neuropathy

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