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. 2024 Dec;19(12):e13164.
doi: 10.1111/ijpo.13164. Epub 2024 Aug 19.

Hair cortisol concentrations are associated with greater adiposity in late adolescence amongst non-Hispanic White individuals

Melissa N Sidote  1 , Nicole Bornkamp  1 , Sheryl L Rifas-Shiman  1   2 , Marie-France Hivert  1   2   3 , Emily Oken  1   2   4 , Amy R Nichols  1   2   4 , Mingyu Zhang  1   2   5
Affiliations

Hair cortisol concentrations are associated with greater adiposity in late adolescence amongst non-Hispanic White individuals

Melissa N Sidote et al. Pediatr Obes. 2024 Dec.

Abstract

Introduction: Hair cortisol concentration (HCC) is a biomarker of long-term stress. Higher HCC is associated with higher adiposity in adults; however, associations are not well characterized in adolescents.

Objective: To examine cross-sectional associations of HCC with adiposity in late adolescence.

Methods: Amongst 336 non-Hispanic White participants (48.5% female, mean 17.7 years) in Project Viva, we used multivariable linear regression models, overall and sex-stratified, to estimate associations of HCC with body mass index (BMI), bioelectric impedance (BIA) percent body fat, waist circumference (WC) and dual X-ray absorptiometry-measured percent and total fat or trunk fat mass. We adjusted models for age and known predictors of adiposity.

Results: Median (interquartile range) HCC was 2.1 pm/mg (1.0-4.5) and mean (SD) BMI was 23.1 kg/m2 (3.9), BIA %body fat 20.2% (9.9) and WC 80.6 cm (10.9). In adjusted models, higher HCC (per doubling) was associated with higher BMI (β = 0.19 kg/m2; 95%CI 0.00, 0.37) and BIA percent body fat (β = 0.41%; 95%CI 0.04, 0.77). We observed no evidence of effect modification by sex.

Conclusions: Higher HCC was associated with greater adiposity in late adolescence. Further research is needed to disentangle the relationship between HCC and adolescent adiposity, including the temporal direction of the relationship and sex-specific associations.

Keywords: adiposity; adolescents; hair cortisol.

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Conflict of interest statement

Conflict of Interest

The authors have no conflicts to declare.

References

    1. Obesity and overweight. Accessed July 3, 2023. https://www.who.int/news-room/fact-sheets/detail/obesity-and-overweight
    1. World Health Organization. Global health risks : mortality and burden of disease attributable to selected major risks. Published online 2009. Accessed July 3, 2023. https://apps.who.int/iris/handle/10665/44203
    1. Llewellyn A, Simmonds M, Owen CG, Woolacott N. Childhood obesity as a predictor of morbidity in adulthood: a systematic review and meta-analysis. Obes Rev Off J Int Assoc Study Obes. 2016;17(1):56–67. doi: 10.1111/obr.12316 - DOI - PubMed
    1. Sommer A, Twig G. The Impact of Childhood and Adolescent Obesity on Cardiovascular Risk in Adulthood: a Systematic Review. Curr Diab Rep. 2018;18(10):91. doi: 10.1007/s11892-018-1062-9 - DOI - PubMed
    1. Tomiyama AJ. Stress and Obesity. Annu Rev Psychol. 2019;70:703–718. doi: 10.1146/annurev-psych-010418-102936 - DOI - PubMed

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