Iohexol versus iopamidol for cervical myelography: a randomised double blind study

Abstract

A randomised double blind trial of iohexol and iopamidol in cervical myelography by both lumbar puncture and direct puncture techniques is reported in one hundred consecutive patients. All patients had EEG examination before and 6-8 h after the myelogram and for each a questionnaire regarding adverse reactions was completed at set intervals. The side effects, radiographic quality of the examination and production of sharp wave activity on EEG were equivalent in the iohexol and iopamidol series. Contrary to previous reports, we consider that iohexol and iopamidol are equally acceptable for all forms of myelography.