Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2024 Aug 5;28(4):388.
doi: 10.3892/etm.2024.12677. eCollection 2024 Oct.

Elective vs. emergency tracheotomy complications in advanced hypopharyngeal cancer

Alina-Georgiana Vulcu Cordunianu  1   2 , Mihai Alexandru Cordunianu  1 , Daniel Cochior  1   3   4   5
Affiliations

Elective vs. emergency tracheotomy complications in advanced hypopharyngeal cancer

Alina-Georgiana Vulcu Cordunianu et al. Exp Ther Med. .

Abstract

Squamous cell carcinoma of the hypopharyngeal region is a rare, aggressive disease with a poor prognosis and a high mortality rate, and represents up to 95% of all hypopharyngeal tumors. Patients with upper aerodigestive tract tumors can develop airway compromise before or during chemoradiotherapy. The present study aims to investigate the complication differences between elective tracheostomy and emergency-setting tracheostomy for patients with advanced hypopharyngeal squamous cell. The study group included 36 patients and analyzed the number and type of complications, functional outcomes and comparation of the laboratory testing in all the patients at 3 specific points (before tracheotomy, during the radiation therapy and at least 3 months after completion of radiation therapy). In addition, univariate analysis was performed in order to evaluate the prognosis of local control rates. The type and number of complications between elective and emergency-setting tracheostomy varied, but all the complications were resolved, and no hypoxic complications secondary to displacement of the tracheostomy tube or death cases related to the tracheostomy occurred. A total of 20/36 patients presented with complications, with 73% (16 patients) from the emergency tracheostomy cohort and 36% (4 patients) from the elective tracheostomy group. More than half of the elective tracheostomy (6/11 patients) responded favorably to the treatment, with a higher frequency than the patients with emergency tracheostomy (5/22 patients). The present study did not encounter significant statistical differences (P>0.05) of the treatment end-result regarding the type of tracheostomy performed, but the prediction analysis found for the patients aged under 60 years old, elective tracheostomy was associated with a higher chance of favorable treatment end result.

Keywords: elective tracheostomy; emergency tracheostomy; hypopharyngeal cancer; organ preservation treatment; squamous cell carcinoma.

PubMed Disclaimer

Conflict of interest statement

The authors declare that they have no competing interests.

References

    1. Vila PM, Uppaluri R. Neoplasms of the hypopharynx and cervical esophagus. In: Cummings Otolaryngology Head and Neck Surgery. Flint PW and Cummings CW (eds). 6th edition, Vol II. Pp1537-1553, Elsevier Saunders, Philadelphia, 2015.
    1. Lewandowska A, Rudzki G, Lewandowski T, Prochnicki M, Rudzki S, Laskowska B, Brudniak J. Quality of life of cancer patients treated with chemotherapy. Int J Environ Res Public Health. 2020;17(6938) doi: 10.3390/ijerph17196938. - DOI - PMC - PubMed
    1. Behrborn H, Kaschke O, Nawka T, Swift A. Ear, Nose, and throat diseases with head and neck surgery. 3th ed. Stuttgart: Thieme, 2009: pp293-329.
    1. Di Credico G, Polesel J, Dal Maso L, Pauli F, Torelli N, Luce D, Radoï L, Matsuo K, Serraino D, Brennan P, et al. Alcohol drinking and head and neck cancer risk: The joint effect of intensity and duration. Br J Cancer. 2020;123:1456–1463. doi: 10.1038/s41416-020-01031-z. - DOI - PMC - PubMed
    1. Larsson LG, Sandström A, Westling P. Relationship of Plummer-Vinson disease to cancer of the upper alimentary tract in Sweden. Cancer Res. 1975;35:3308–3316. - PubMed

LinkOut - more resources