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. 2024 Aug;27(8):e15295.
doi: 10.1111/1756-185X.15295.

Effect of the Janus kinase inhibitor tofacitinib in the treatment of juvenile scleroderma: A single-center experience

Lara Colussi  1 , Arianna Dagri  2 , Serena Pastore  3 , Alberto Tommasini  1   3 , Alessia Pin  3 , Andrea Taddio  1   3
Affiliations

Effect of the Janus kinase inhibitor tofacitinib in the treatment of juvenile scleroderma: A single-center experience

Lara Colussi et al. Int J Rheum Dis. 2024 Aug.
No abstract available

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References

REFERENCES

    1. Li SC. Scleroderma in children and adolescents: localized scleroderma and systemic sclerosis. Pediatr Clin N Am. 2018;65(4):757‐781. doi:10.1016/j.pcl.2018.04.002
    1. McGaugh S, Kallis P, de Benedetto A, Thomas RM. Janus kinase inhibitors for treatment of morphea and systemic sclerosis: a literature review. Dermatol Ther. 2022;35(6):e15437. doi:10.1111/dth.15437
    1. Wang W, Bhattacharyya S, Marangoni RG, et al. The JAK/STAT pathway is activated in systemic sclerosis and is effectively targeted by tofacitinib. J Scleroderma Relat Disord. 2020;5(1):40‐50. doi:10.1177/2397198319865367
    1. Moriana C, Moulinet T, Jaussaud R, Decker P. JAK inhibitors and systemic sclerosis: a systematic review of the literature. Autoimmun Rev. 2022;21(10):103168. doi:10.1016/j.autrev.2022.103168
    1. George R, George A, Kumar TS. Update on management of morphea (localized scleroderma) in children. Indian Dermatol Online J. 2020;11(2):135‐145. doi:10.4103/idoj.IDOJ_284_19

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