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Case Reports
. 2024 Jul 8:51:1-3.
doi: 10.1016/j.jdcr.2024.06.015. eCollection 2024 Sep.

Drug reaction with eosinophilia and systemic symptoms secondary to minocycline complicated by posterior reversible encephalopathy syndrome

Cheney Jianlin Wong  1 , Angelyn Chen Yin Lua  1 , Yong-Kwang Tay  1 , Sze Hwa Tan  2 , Ratna Rajaratnam  1
Affiliations
Case Reports

Drug reaction with eosinophilia and systemic symptoms secondary to minocycline complicated by posterior reversible encephalopathy syndrome

Cheney Jianlin Wong et al. JAAD Case Rep. .
No abstract available

Keywords: drug reaction with eosinophilia and systemic symptoms; minocycline; posterior reversible encephalopathy syndrome.

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Conflict of interest statement

None disclosed.

Figures

Fig 1
Fig 1
A, Confluent urticated plaques on face and chest. B, Confluent urticated plaques on anterior trunk.
Fig 2
Fig 2
Histopathological exam with hematoxylin and eosin stain (original magnification ×100). The epidermis shows spongiotic changes while the dermis shows perivascular inflammation composed of lymphocytes, histiocytes, and some eosinophils.
Fig 3
Fig 3
Brain magnetic resonance imaging (MRI) showing extensive T2-weighted hyperintensities involving both cortical/subcortical cerebral regions (black arrows).
See this image and copyright information in PMC

References

    1. Shiohara T., Mizukawa Y. Drug-induced hypersensitivity syndrome (DiHS)/drug reaction with eosinophilia and systemic symptoms (DRESS): an update in 2019. Allergol Int. 2019;68(3):301–308. doi: 10.1016/j.alit.2019.03.006. - DOI - PubMed
    1. Shankar J., Banfield J. Posterior reversible encephalopathy syndrome: a review. Can Assoc Radiol J. 2017;68(2):147–153. doi: 10.1016/j.carj.2016.08.005. - DOI - PubMed
    1. Garrido-Mesa N., Zarzuelo A., Gálvez J. Minocycline: far beyond an antibiotic. Br J Pharmacol. 2013;169(2):337–352. doi: 10.1111/bph.12139. - DOI - PMC - PubMed
    1. Ochsendorf F. Minocycline in acne vulgaris. Am J Clin Dermatol. 2010;11(5):327–341. doi: 10.2165/11319280-000000000-00000. - DOI - PubMed
    1. Sabile J.M., Grider D.J., Prickett K.A., Li H., Mallidi P.V. Posterior reversible encephalopathy syndrome (PRES) and drug-induced hypersensitivity syndrome (DIHS) following immunotherapy and BRAF/MEK inhibition with continued response in metastatic melanoma. Case Rep Oncol Med. 2021;2021:1–5. doi: 10.1155/2021/8845063. - DOI - PMC - PubMed

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