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. 2024 Jul 31;58(13):81-86.
doi: 10.47895/amp.v58i13.8161. eCollection 2024.

Clinical Course of Healthcare Workers Diagnosed as COVID-19 Suspects and Contacts during the Coronavirus Disease 2019 Pandemic: A Cross-sectional Study

Marianne M Sadaya  1 , Geannagail O Anuran  1
Affiliations

Clinical Course of Healthcare Workers Diagnosed as COVID-19 Suspects and Contacts during the Coronavirus Disease 2019 Pandemic: A Cross-sectional Study

Marianne M Sadaya et al. Acta Med Philipp. .

Abstract

Background: COVID-19 infection can present in various clinical forms. Anosmia has been significantly associated with a positive RT-PCR, but it usually appears after four days and has also been observed among COVID-19 negative patients. Knowledge on the clinical course of COVID-19 can guide decision-making on screening, diagnostic testing, and quarantine/isolation procedures.

Objectives: To describe the clinical course of healthcare workers (HCWs) with COVID-19-related exposure, symptoms, differential diagnoses, and time to return to work clearance.

Methods: This was a cross-sectional study involving HCWs diagnosed as COVID-19 contacts/suspects between April 2020 and April 2021. Information on demographics, time elapsed between clinical events, outcomes, and final diagnoses were collected from hospital records. Categorical data was presented in frequencies and percentages, while numerical data were reported as range and median values.

Results: There were 4755 consultations for COVID-19-related symptoms or exposure that were included in the study. Symptoms developed at a median of one day post-exposure. Consultation was at two days following symptom onset or four days after exposure. RT-PCR was done on the day of consult. Symptoms resolved after a median of six days. Return to work (RTW) was seven days from consult. Common presenting symptoms were respiratory (56.71%) and systemic (34.04%). COVID-19 was positive in 13.79% of consults. Almost all HCWs recovered (99%) as outpatient (88%). Differential diagnoses were usually other respiratory infections (8.60%) and allergic rhinitis (2.37%).

Conclusion: The clinical course for HCWs who consulted for COVID-19-related symptoms or exposure lasted for two weeks from symptom onset or exposure until clearance for work resumption. The most common symptoms were respiratory and systemic in nature. Recovery was noted after six days. The most common alternative diagnoses for COVID-19 negative cases were respiratory infection and allergic rhinitis.

Keywords: COVID-19; clinical course; healthcare worker.

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Conflict of interest statement

Both authors declared no conflicts of interest.

Figures

Figure 1
Figure 1
Most common COVID-19-related symptoms reported on initial consultation by HCWs in a tertiary hospital from April 2020-2021 (n=4755).
See this image and copyright information in PMC

References

    1. Zhou R, Li F, Chen F, Liu H, Zheng J, Lei C, et al. . Viral dynamics in asymptomatic patients with COVID-19. Int J Infect Dis. 2020. Jul;96:288–90. doi: 10.1016/j.ijid.2020.05.030. PMID: 32437933; PMCID: . - DOI - PMC - PubMed
    1. World Health Organization (WHO) . Modes of transmission of virus causing COVID-19: implications for IPC precaution recommendations (Scientific Brief) [Internet]. 2020. Mar [cited 2022 June]. Available from: https://www.who.int/news-room/commentaries/detail/modes-of-transmission-...
    1. Huang L, Zhang X,Zhang X, Wei Z, Zhang L, Xu J, et al. . Rapid asymptomatic transmission of COVID-19 during the incubation period demonstrating strong infectivity in a cluster of youngsters aged 16-23 years outside Wuhan and characteristics of young patients with COVID-19: a prospective contact-tracing study. J Infect. 2020. Jun;80(6): e1-e13. doi: 10.1016/j.jinf.2020.03.006. PMID: 32283156; PMCID: . - DOI - PMC - PubMed
    1. Rothe C, Schunk M, Sothmann P, Bretzel G, Froeschl G, Wallrauch C, et al. . Transmission of 2019-nCoV infection from an asymptomatic contact in Germany. N Engl J Med. 2020. Mar 5;382(10):970-1. doi: 10.1056/NEJMc2001468. PMID: 32003551; PMCID: . - DOI - PMC - PubMed
    1. Liu M, He P, Liu HG, Wang XJ, Li FJ, Chen S, et al. . [Clinical characteristics of 30 medical workers infected with new coronavirus pneumonia]. PubMed [Internet]. 2020. Feb 17;43(0):E016. Available from: https://pubmed.ncbi.nlm.nih.gov/32062957. - PubMed

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